Psoriasin/S100A7 Protein, Human, Recombinant

Protein S100-A7, also known as S100 calcium-binding protein A7, Psoriasin, S100A7, and PSOR1, is a secreted protein which belongs to theS-100 family. S100A7 was first isolated from skin involved by psoriasis, which can be induced in cultured squamous epithelial cells. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation. S100A7 plays a role in the pathogenesis of inflammatory skin disease, as a chemotactic factor for hematopoietic cells. It also plays a role in early stages of breast tumor progression in association with the development of the invasive phenotype.

Psoriasin/S100A7 Protein, Human, Recombinant

パッケージサイズ	在庫状況	単価(税別)
50 μg	約5 days	￥ 138,000

バルクのお問い合わせ

説明

Species	Human
Expression Host	E. coli
Tag	Tag Free
Accession Number	P31151
別名	S100 calcium binding protein A7, PSOR1, S100A7c
Construction	native Human S100A7 (NP_002954.2) (Met 1-Gln 101)
Protein Purity	> 98 % as determined by SDS-PAGE
分子量	11.6 kDa (predicted)

Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Protein S100-A7, also known as S100 calcium-binding protein A7, Psoriasin, S100A7, and PSOR1, is a secreted protein which belongs to theS-100 family. S100A7 was first isolated from skin involved by psoriasis, which can be induced in cultured squamous epithelial cells. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation. S100A7 plays a role in the pathogenesis of inflammatory skin disease, as a chemotactic factor for hematopoietic cells. It also plays a role in early stages of breast tumor progression in association with the development of the invasive phenotype.

参考文献

1. Miyasaki, KT. et al., 1993, J. Dent. Res. 72: 517-23. 2. Watson, PH. et al., 1998, Int J Biochem Cell Biol 30 (5):567-71. 3. Emberley, ED. et al., 2004, Breast Cancer Res 6 (4): 153-9. 4. Ohuchida, K. et al., 2006, Clin Cancer Res 12 (18):5417-22. 5. Kouno, T. et al., 2008, J Pept Sci. 14 (10):1129-38.León, R. et al., 2009, Biochemistry. 48 (44): 10591-600.

Calculator

Reconstitution Calculator

Recombinant Proteins Dilute Calculator

Specific Activity Calculator

bottom

Psoriasin/S100A7 Protein, Human, Recombinant

参考文献

Calculator

技術サポート

Keywords