RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)
カタログ番号 TMPJ-00349
別名:
CD265 antigen, FEO, TRANCER, ODFR, ODFROSTS, TRANCE R, TNFRSF11A, OFE, OPTB7, CD265, PDB2, receptor activator of nuclear factor-κ B, RANK1, tumor necrosis factor receptor superfamily member 11A, receptor activator of nuclear factor-kappa B, Receptor activator of NF-KB
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas.
All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)
| パッケージサイズ |
在庫状況 |
単価(税別) |
| 10 μg |
約5 days |
￥ 25,500 |
| 50 μg |
約5 days |
￥ 71,500 |
| 500 μg |
約5 days |
￥ 298,500 |
| 1 mg |
約5 days |
￥ 454,500 |
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生物学的特性に関する説明
Technical Params
Product Properties
| 説明 |
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas. |
| Species |
Human
|
| Expression Host |
HEK293 Cells
|
| Tag |
C-6xHis
|
| Accession Number |
Q9Y6Q6
|
| 別名 |
CD265 antigen, FEO, TRANCER, ODFR, ODFROSTS, TRANCE R, TNFRSF11A, OFE, OPTB7, CD265, PDB2, receptor activator of nuclear factor-κ B, RANK1, tumor necrosis factor receptor superfamily member 11A, receptor activator of nuclear factor-kappa B, Receptor activator of NF-KB
|
| Amino Acid |
Ile30-Pro212
|
| Construction |
Ile30-Pro212
|
| Protein Purity |
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
|
| 分子量 |
25-30 KDa (reducing condition)
|
| Endotoxin |
< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
|
| Formulation |
Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
|
| Reconstitution |
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
|
| Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
|
| Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
|
| Research Background |
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas.
|
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技術サポート
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Keywords
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)
CD265 antigen
FEO
RANK 1
TRANCER
ODFR
OPTB 7
ODFROSTS
OPTB-7
TRANCE R
PDB 2
TNFRSF11A
CD 265
OFE
OPTB7
CD265
PDB2
RANK-1
CD-265
receptor activator of nuclear factor-k B
PDB-2
receptor activator of nuclear factor-κ B
RANK1
tumor necrosis factor receptor superfamily member 11A
receptor activator of nuclear factor-kappa B
Receptor activator of NF-KB
recombinant
recombinant-proteins
proteins
protein
