S100A5 Protein, Mouse, Recombinant (His)

S100A5 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 12.3 kDa and the accession number is P63084.

S100A5 Protein, Mouse, Recombinant (His)

パッケージサイズ	在庫状況	単価(税別)
100 μg	約5 days	￥ 138,000

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説明	S100A5 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 12.3 kDa and the accession number is P63084.

Species	Mouse
Expression Host	E. coli
Tag	His
Accession Number	P63084
別名	S100 calcium binding protein A5, S100D9
Construction	The Mouse S100A5 (P63084) (Met 1-Lys 93) was expressed, with a polyhistide tag at the N-terminus.
Protein Purity	> 97 % as determined by SDS-PAGE
分子量	12.3 kDa (predicted)

Endotoxin	Please contact us for more information.
Formulation	Supplied as sterile 50 mM Tris, 20% glycerol, pH 7.5.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the?neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S100-A5, also known as Protein S-100D, S100 calcium-binding protein A5, S100A5 and S100D, is a member of the S100 family which contains two EF-hand domains. S100A5 is also a novel member of the EF-hand superfamily of calcium-binding proteins that is poorly characterized at the protein level. It is expressed in very restricted regions of the adult brain. From birth onwards, S100A5 remained a neuronal-specific protein, only located in a subpopulation of neurons in the spiral ganglion.

参考文献

1. Sch?fer,B.W. et al., 2000, J Biol Chem. 275 (39):30623-30. 2. Gebhardt, C. et al., 2006, Biochem Pharmacol. 72 (11):1622-31. 3. Nonaka, D. et al., 2008, J. Cutan. Pathol. 35 (11): 1014-9. 4. Lim, SY. et al., 2008, J Immunol. 181 (8): 5627-36. 5. Heibeck TH. et al., 2009, J. Proteome Res. 8:3852-61.

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S100A5 Protein, Mouse, Recombinant (His)

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