S100A6 Protein, Mouse, Recombinant

S100A6 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 10 kDa and the accession number is P14069.

S100A6 Protein, Mouse, Recombinant

パッケージサイズ	在庫状況	単価(税別)
50 μg	約5 days	￥ 138,000

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説明	S100A6 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 10 kDa and the accession number is P14069.

Species	Mouse
Expression Host	E. coli
Tag	Tag Free
Accession Number	P14069
別名	2A9, PRA, 5B10, S100 calcium binding protein A6, Cacy, CALCYCLIN
Construction	Mouse S100A6 (NP_035443.1) (Met 1-Lys 89)
Protein Purity	> 98 % as determined by SDS-PAGE
分子量	10 kDa (predicted)

Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. S100A6 (S100 calcium-binding protein A6) is a member of the S100 family of proteins, and functions in prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of S100A6 have been implicated in melanoma.

参考文献

1. Schäfer, B.W. et al., 1996, Trends Biochem. Sci. 21 (4): 134-140. 2. Donato,R. et al., 2003, Microsc. Res. Tech. 60 (6): 540-551. 3. Nowotny, M. et al., 2003, J. Biol. Chem. 278 (29): 26923-26928. 4. Nonaka D, et al., 2008, J. Cutan. Pathol. 35 (11): 1014-1019. 5. Marenholz, I. et al., 2004, Biochem. Biophys. Res. Commun. 322 (4): 1111-22.

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S100A6 Protein, Mouse, Recombinant

参考文献

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