SEMA7A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.5 kDa and the accession number is Q9QUR8.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
100 μg | 約5 days | ¥ 77,500 |
500 μg | 約5 days | ¥ 310,000 |
1 mg | 約5 days | ¥ 516,500 |
説明 | SEMA7A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.5 kDa and the accession number is Q9QUR8. |
Species | Mouse |
Expression Host | HEK293 Cells |
Tag | C-His |
Accession Number | Q9QUR8 |
別名 | Sema7A, H-SEMA-K1, JMH, Semaphorin-K1, Semaphorin-L, CD108, H-Sema-L, SEMAK1, MGC126692, CD108MGC126696, SEMAL, CDw108, Sema L, Semaphorin-7A |
Construction | Gln45-Ala646 |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
分子量 | 69.5 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 200 mM L-arginine (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | Semaphorin7A (Sema7A) plays an important role in the immunoregulation of the brain.Sema7A is upregulated in the epileptic brain and plays a potential role in the regulation of seizure activity in PTZ-kindled epileptic rats, which may be related to neuroinflammation. Sema7A promotes the inflammatory cytokines TNF-α and IL-6 as well as the growth of mossy fibers through the ERK pathway, suggesting that Sema7A may promote seizures by increasing neuroinflammation and activating pathological neural circuits. Sema7A plays a critical role in epilepsy and could be a potential therapeutic target for this neurological disorder. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
SEMA7A Protein, Mouse, Recombinant (His) Sema7A H-SEMA-K1 JMH Semaphorin-K1 Semaphorin-L CD108 H-Sema-L SEMAK1 MGC126692 MGC 126692 CD108MGC126696 MGC-126692 CD 108 CD-108 SEMAL CD108MGC 126696 CDw108 Sema L SEMAK 1 SEMAK-1 CD108MGC-126696 Semaphorin-7A recombinant recombinant-proteins proteins protein