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Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi)

カタログ番号 TMPK-01295
別名: CD33 molecule-like 3, Siglec15, CD33 antigen-like 3, HsT1361, SIGLEC-15, CD33L3

Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 29.2 kDa and the accession number is XP_005586866.2.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi)
パッケージサイズ 在庫状況 単価(税別)
100 μg 約5 days ¥ 112,000
500 μg 約5 days ¥ 447,500
1 mg 約5 days ¥ 746,000
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 29.2 kDa and the accession number is XP_005586866.2.
Species Cynomolgus
Expression Host HEK293 Cells
Tag C-His-Avi
Accession Number XP_005586866.2
別名 CD33 molecule-like 3, Siglec15, CD33 antigen-like 3, HsT1361, SIGLEC-15, CD33L3
Construction Met60-Thr322
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量 29.2 kDa (predicted). Due to glycosylation, the protein migratesto 33-43 kDa based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Supplied as 0.22 μm filtered solution in 20 mM PB, 500 mM NaCl, 0.1M L-arginine (pH 6.0).
Stability & Storage

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.

参考文献

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Keywords

Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi) SIGLEC 15 SIGLEC15 CD33 molecule-like 3 Siglec15 CD33 antigen-like 3 HsT 1361 HsT1361 SIGLEC-15 CD33L3 HsT-1361 recombinant recombinant-proteins proteins protein