SLAMF5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-43 KDa and the accession number is Q9UIB8.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
10 μg | 約5 days | ¥ 25,500 |
50 μg | 約5 days | ¥ 71,500 |
500 μg | 約5 days | ¥ 319,000 |
1 mg | 約5 days | ¥ 454,500 |
説明 | SLAMF5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-43 KDa and the accession number is Q9UIB8. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-6xHis |
Accession Number | Q9UIB8 |
別名 | SLAMF5, Signaling lymphocytic activation molecule 5, Hly9-β, Cell surface antigen MAX.3, Leukocyte differentiation antigen CD84, CD84, SLAM family member 5, Hly9-beta |
Amino Acid | Lys22-Arg220 |
Construction | Lys22-Arg220 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 35-43 KDa (reducing condition) |
Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | SLAM family member 5 (SLAMF5/CD84) is a type I transmembrane protein in the SLAM subgroup of the CD2 family. SLAM family proteins regulate multiple aspects of immune system function. Mature human CD84 consists of a 204 amino acid (aa) extracellular domain (ECD) with two Iglike domains,a 21 aa transmembrane segment, and a 99 aa cytoplasmic domain with two immunoreceptor tyrosinebased switch motifs (ITSMs). CD84 exhibits homophilic binding which is mediated by the N-terminal Ig-like domain. Ligation induces tyrosine phosphorylation in the cytoplasmic ITSMs which then recruit the signaling adaptor molecules SAP (SLAM-associated protein) and EAT-2(EWS/Fli1-activated transcript 2).CD84 signaling inhibits Fc epsilon RI-induced mast cell activation but enhances platelet activation. LPS-induced macrophage activation,T cell proliferation and IFN-γproduction, and the interactions between T cells and B cells that are required for germinal center formation. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
SLAMF5 Protein, Human, Recombinant (His) CD-84 SLAMF-5 SLAMF5 SLAMF 5 Signaling lymphocytic activation molecule 5 Hly9-β CD 84 Cell surface antigen MAX.3 Leukocyte differentiation antigen CD84 CD84 SLAM family member 5 Hly9-beta recombinant recombinant-proteins proteins protein