SNCA Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 KDa and the accession number is O55042.
| 説明 |
SNCA Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 KDa and the accession number is O55042. |
| Species |
Mouse
|
| Expression Host |
E. coli
|
| Tag |
Tag Free
|
| Accession Number |
O55042
|
| 別名 |
NACP, α-synuclein, Non-A beta component of AD amyloid, Non-A β component of AD amyloid, Snca, Alpha-synuclein, Non-A4 component of amyloid precursor
|
| Amino Acid |
Met1-Ala140
|
| Construction |
Met1-Ala140
|
| Protein Purity |
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
|
| 分子量 |
17 KDa (reducing condition)
|
| Endotoxin |
< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
|
| Formulation |
Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
|
| Reconstitution |
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
|
| Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
|
| Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
|
| Research Background |
Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).
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