High expression of STAT4 in gastric cancer predicted a better clinical outcome. STAT4 might be a useful biomarker to identify patients at high risk of recurrence after gastrectomy. Genetic variants in the transcription factor STAT4 are associated with increased susceptibility to systemic lupus erythematosus (SLE) and a more severe disease phenotype.
説明 | High expression of STAT4 in gastric cancer predicted a better clinical outcome. STAT4 might be a useful biomarker to identify patients at high risk of recurrence after gastrectomy. Genetic variants in the transcription factor STAT4 are associated with increased susceptibility to systemic lupus erythematosus (SLE) and a more severe disease phenotype. |
Species | Human |
Expression Host | Baculovirus Insect Cells |
Tag | His |
Accession Number | Q14765 |
別名 | signal transducer and activator of transcription 4, SLEB11 |
Construction | The Human STAT4 (Q14765) (Met 1-Glu 748) was expressed, with a polyhistidine tag at the N-terminus. |
Protein Purity | > 85 % as determined by SDS-PAGE |
分子量 | 88 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 20% glycerol, 0.5 mM DTT. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | High expression of STAT4 in gastric cancer predicted a better clinical outcome. STAT4 might be a useful biomarker to identify patients at high risk of recurrence after gastrectomy. Genetic variants in the transcription factor STAT4 are associated with increased susceptibility to systemic lupus erythematosus (SLE) and a more severe disease phenotype. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
STAT4 Protein, Human, Recombinant (His) signal transducer and activator of transcription 4 SLEB 11 SLEB11 SLEB-11 recombinant recombinant-proteins proteins protein