STC2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.7 kDa and the accession number is O76061.
説明 | STC2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.7 kDa and the accession number is O76061. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-hFc |
Accession Number | O76061 |
別名 | STC-2, STCRP, stanniocalcin 2 |
Construction | The Human STC2 (O76061) (Met1-Arg302) was expressed with the Fc region of Human IgG1 at the C-terminus. |
Protein Purity | > 85 % as determined by SDS-PAGE |
分子量 | 57.7 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | STC2 is a secreted, homodimeric glycoprotein expressed in a wide variety of tissues. STC2 has an anti-hypocalcemic action on calcium and phosphate homeostasis. It may have autocrine or paracrine functions. Its C-terminus contains a cluster of histidine residues that may interact with metal ions. STC2 has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. It may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
STC2 Protein, Human, Recombinant (hFc) STC 2 STC-2 STC2 STCRP stanniocalcin 2 recombinant recombinant-proteins proteins protein