Syndecan-1 Protein, Human, Recombinant (aa 23-254, His)

Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver. Syndecan-1 Protein, Human, Recombinant (aa 23-254, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 25 kDa and the accession number is AAH08765.

Syndecan-1 Protein, Human, Recombinant (aa 23-254, His)

パッケージサイズ	在庫状況	単価(税別)
100 μg	約5 days	￥ 112,000
500 μg	約5 days	￥ 447,500
1 mg	約5 days	￥ 746,000

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説明

Species	Human
Expression Host	HEK293 Cells
Tag	C-His
Accession Number	AAH08765
別名	Syndecan-1, CD138, SDC, SYND1, SDC1
Construction	Gln23-Gly254
Protein Purity	> 95% as determined by Tris-Bis PAGE
分子量	25 kDa (predicted). Due to glycosylation, the protein migrates to 50-80 kDa based on Tris-Bis PAGE result.

Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver.

参考文献

1. Regős E, et al. Syndecan-1 in Liver Diseases. Pathol Oncol Res. 2020 Apr;26(2):813-819. doi: 10.1007/s12253-019-00617-0. Epub 2019 Mar 2. PMID: 30826971; PMCID: PMC7242248.

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Syndecan-1 Protein, Human, Recombinant (aa 23-254, His)

参考文献

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