Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domain. The C-terminal domain forms a four-stranded coiled coil. Thymopentin may be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. It is associated with T-cell development and function. Meantime, Thymopentin plays an important role, together with LMNA, in the nuclear anchorage of RB1. Thymopoietin is participated in the induction of CD90 in the thymus.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
10 μg | 約5 days | ¥ 30,000 |
50 μg | 約5 days | ¥ 89,500 |
500 μg | 約5 days | ¥ 436,000 |
1 mg | 約5 days | ¥ 626,500 |
説明 | Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domain. The C-terminal domain forms a four-stranded coiled coil. Thymopentin may be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. It is associated with T-cell development and function. Meantime, Thymopentin plays an important role, together with LMNA, in the nuclear anchorage of RB1. Thymopoietin is participated in the induction of CD90 in the thymus. |
Species | Human |
Expression Host | E. coli |
Tag | C-6xHis |
Accession Number | P42167 |
別名 | Thymopoietin-Related Peptide Isoforms β/γ, Splenin, TMPO, TP, TP5, LAP2, Lamina-Associated Polypeptide 2 Isoforms Beta/Gamma, TPRP Isoforms β/γ, Thymopentin, Thymopoietin-Related Peptide Isoforms Beta/Gamma, Thymopoietin Isoforms Beta/Gamma, TP β/γ, TP Beta/γ, Lamina-Associated Polypeptide 2 Isoforms β/γ, Thymopoietin, TPRP Isoforms Beta/Gamma, Thymopoietin Isoforms β/γ, TP Beta/Gamma |
Amino Acid | Met1-Glu187 |
Construction | Met1-Glu187 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 27 KDa (reducing condition) |
Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domain. The C-terminal domain forms a four-stranded coiled coil. Thymopentin may be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. It is associated with T-cell development and function. Meantime, Thymopentin plays an important role, together with LMNA, in the nuclear anchorage of RB1. Thymopoietin is participated in the induction of CD90 in the thymus. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
TMPO Protein, Human, Recombinant (His) LAP-2 Thymopoietin-Related Peptide Isoforms β/γ Splenin TP-5 TMPO TP TP5 LAP2 Lamina-Associated Polypeptide 2 Isoforms Beta/Gamma TPRP Isoforms β/γ Thymopentin Thymopoietin-Related Peptide Isoforms Beta/Gamma TP 5 LAP 2 Thymopoietin Isoforms Beta/Gamma TP β/γ TP Beta/γ Lamina-Associated Polypeptide 2 Isoforms β/γ Thymopoietin TPRP Isoforms Beta/Gamma Thymopoietin Isoforms β/γ TP Beta/Gamma recombinant recombinant-proteins proteins protein