Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
10 μg | 約5 days | ¥ 6,500 |
50 μg | 約5 days | ¥ 24,000 |
500 μg | 約5 days | ¥ 100,000 |
1 mg | 約5 days | ¥ 142,500 |
説明 | Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. |
Species | Human |
Expression Host | E. coli |
Tag | N-GST |
Accession Number | P51668 |
別名 | Ubiquitin-conjugating enzyme E2(17)KB 1, UB, UbcH5, UBC5A, Stimulator of Fe transport, Ubiquitin carrier protein D1, Ubiquitin-conjugating enzyme E2-17 kDa 1, UBC4/5 homolog, Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-protein ligase D1, SFT |
Amino Acid | Met1-Met147 |
Construction | Met1-Met147 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 40 KDa (reducing condition) |
Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10% Glycerol, pH 7.5. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
UBE2D1 Protein, Human, Recombinant (GST) Ubiquitin-conjugating enzyme E2(17)KB 1 UB UbcH5 UBC5A Stimulator of Fe transport Ubiquitin carrier protein D1 Ubiquitin-conjugating enzyme E2-17 kDa 1 UBC4/5 homolog Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-protein ligase D1 SFT recombinant recombinant-proteins proteins protein