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UROD Protein, Human, Recombinant (His)

カタログ番号 TMPJ-00788
別名: UPD, UROD, Uroporphyrinogen Decarboxylase, URO-D

Uroporphyrinogen decarboxylase (UROD), is an enzyme of the heme biosynthetic pathway which belongs to the uroporphyrinogen decarboxylase family. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. UROD is a homodimeric enzyme that catalyzes the fifth step in heme biosynthesis: the elimination of carboxyl groups from the four acetate side chains of uroporphyrinogen III to yield coproporphyrinogen III. Defects in UROD are the cause of familial porphyria cutanea tarda (FPCT) and hepatoerythropoietic porphyria (HEP).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
UROD Protein, Human, Recombinant (His)
パッケージサイズ 在庫状況 単価(税別)
10 μg 約5 days ¥ 42,500
50 μg 約5 days ¥ 125,000
500 μg 約5 days ¥ 436,000
1 mg 約5 days ¥ 626,500
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生物学的特性に関する説明
Technical Params
Product Properties
説明 Uroporphyrinogen decarboxylase (UROD), is an enzyme of the heme biosynthetic pathway which belongs to the uroporphyrinogen decarboxylase family. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. UROD is a homodimeric enzyme that catalyzes the fifth step in heme biosynthesis: the elimination of carboxyl groups from the four acetate side chains of uroporphyrinogen III to yield coproporphyrinogen III. Defects in UROD are the cause of familial porphyria cutanea tarda (FPCT) and hepatoerythropoietic porphyria (HEP).
Species Human
Expression Host E. coli
Tag N-6xHis
Accession Number P06132
別名 UPD, UROD, Uroporphyrinogen Decarboxylase, URO-D
Amino Acid Met1-Asn367
Construction Met1-Asn367
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 40 KDa (reducing condition)
Endotoxin < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, 1 mM DTT, 1 mM EDTA, pH 8.0.
Stability & Storage

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Uroporphyrinogen decarboxylase (UROD), is an enzyme of the heme biosynthetic pathway which belongs to the uroporphyrinogen decarboxylase family. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. UROD is a homodimeric enzyme that catalyzes the fifth step in heme biosynthesis: the elimination of carboxyl groups from the four acetate side chains of uroporphyrinogen III to yield coproporphyrinogen III. Defects in UROD are the cause of familial porphyria cutanea tarda (FPCT) and hepatoerythropoietic porphyria (HEP).

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Keywords

UROD Protein, Human, Recombinant (His) UPD UROD Uroporphyrinogen Decarboxylase URO-D recombinant recombinant-proteins proteins protein