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カタログ番号 | 製品名 | 別名 | ターゲット |
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T39594 | AKR1B10-IN-1 | AKR1B10-IN-1 | |
AKR1B10-IN-1, a powerful AKR1B10 (Aldo-Keto Reductase 1B10) inhibitor, demonstrates an IC50 value of 3.5 nM. This compound effectively curtails the proliferation, metastasis, and Cisplatin (CDDP) resistance of lung cance... | |||
T9406 | Phenethyl trans-cinnamate | Others | |
Phenethyl trans-cinnamate is an aromatic ester found in various plants. It is an important intermediate in the synthesis of various drugs and spices, and is also used in the synthesis of various flavors, fragrances and c... | |||
T15281 | Fidarestat | SNK 860 | Reductase |
Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively). It has the potential to treat diabetic disease. | |||
T28056 | MK319 | MK 319,MK-319 | |
MK319 is an AKR1B10 inhibitor. | |||
T28054 | MK181 | MK 181,MK-181 | |
MK181 is an inhibitor of AKR1B10, a tumor marker and promising antineoplastic target. | |||
T28055 | MK204 | MK-204,MK 204 | |
MK204 is an inhibitor of AKR1B10, a tumor marker and promising antineoplastic target. |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-02438 | AKR1B1 Protein, Human, Recombinant (His) | Human | E. coli |
Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest... |