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Search Results for " Calcitonin "

ターゲット

53

阻害剤

3

天然化合物

11

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
TP1040 Calcitonin (salmon) Calcitonin salmon,Salmon calcitonin CGRP Receptor
Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause.
TP1040L Calcitonin(salmon) Acetate(47931-85-1(free base)) Salmon calcitonin CGRP Receptor
Calcitonin(salmon)Acetate(47931-85-1(free base))(Salmon calcitonin) , a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause.
TP1028L Calcitonin eel acetate Calcitonin eel acetate (57014-02-5 Free base),Thyrocalcitonin eel Others
Calcitonin eel acetate (Calcitonin eel acetate (57014-02-5 Free base)) is the regulation of calcium homeostasis thyroid hormone peptide.
TP2055 Calcitonin (human)
Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.
T37413 Calcitonin (salmon) (trifluoroacetate salt)
Calcitonin is a peptide hormone that lowers blood calcium level and inhibits bone resorption. It belongs to the calcitonin family of peptides, which also includes amylin , calcitonin gene-related peptide , and adrenomedu...
TP1028 Calcitonin, eel Thyrocalcitonin eel
Calcitonin, eel is a peptide hormone that plays a crucial role in maintaining calcium balance within the body. It is extensively utilized in the scientific investigation of postmenopausal osteoporosis, a condition charac...
TP1027 Calcitonin, eel TFA (57014-02-5 free base) Thyrocalcitonin eel (TFA),Calcitonin, eel TFA
Calcitonin,eel TFA is a thyroid hormone polypeptide that can regulate calcium homeostasis and is widely used in the study of postmenopausal osteoporosis.
T78372 Calcitonin, eel TFA Thyrocalcitonin eel TFA
Calcitonin (eel TFA) is a thyroid hormone peptide that plays a role in regulating calcium homeostasis and is commonly utilized in the study of postmenopausal osteoporosis [1].
TP1200 CGRP (83-119), rat TFA Calcitonin Gene Related Peptide(83-119), rat TFA Others
CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.
TP1677 Calcitonin (8-32), salmon
Calcitonin (8-32), salmon is a highly selective amylin receptor antagonist.Calcitonin is a hormone known to participate in calcium and phosphorus metabolism. In mammals, the major source of calcitonin is from the parafol...
TP1202 Calcitonin Gene Related Peptide (CGRP) II, rat CGRP II, rat
Calcitonin Gene Related Peptide II is a potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes.
T76032 Calcitonin Gene Related Peptide (CGRP) II, rat TFA
Calcitonin Gene-Related Peptide (CGRP) II, rat TFA, functions as a potent and enduring vasodilator by activating CGRP receptors. This compound is utilized in cardiovascular disease research [1].
T76363 [Tyr22] Calcitonin Gene Related Peptide, (22-37), rat
[Tyr22] Calcitonin Gene Related Peptide (22-37), rat, refers to a fragment (amino acids 22-37) of the rat calcitonin gene-related peptide (CGRP) that targets the CGRP receptor and adenylate cyclase. While calcitonin is p...
TP1203 CGRP(83-119), rat Calcitonin Gene Related Peptide (CGRP) (83-119), rat
Calcitonin Gene Related Peptide (CGRP) (83-119), rat is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.
T17194 Ubrogepant MK-1602 CGRP Receptor
Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.
TP1201 CGRP II, rat (TFA) (99889-63-1 free base) Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA)
Calcitonin Gene Related Peptide (CGRP) II, rat (TFA) is a neuropeptide with 37 amino acid.
T12293L Olcegepant BIBN-4096,BIBN 4096BS CGRP Receptor
Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP).
T4610 Rimegepant BMS 927711,BMS-927711,BMS927711,BHV-3000 CGRP Receptor
Rimegepant (BMS 927711) is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM.
T8682 Vazegepant hydrochloride Vazegepant HCl CGRP Receptor
Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.
T6590 MK-3207 Hydrochloride MK-3207 HCl CGRP Receptor
MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2.
TP2233L CGRP (rat) acetate Others
CGRP (rat) acetate is a calcitonin gene-related peptide (CGRP). CGRP (rat) acetate is a potent vasodilator.
TP1134L HCGRP-(8-37) acetate HCGRP-(8-37) acetate (119911-68-1 free base) CGRP Receptor
HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor.
T76874 Erenumab AMG-334 CGRP Receptor
Erenumab is a whole-human monoclonal antibody. Erenumab inhibits calcitonin gene-related peptide (CGRP) receptors. Erenumab can be used to prevent migraine attacks.
TP1257L Adrenomedullin (AM) (22-52), human acetate Adrenomedullin (AM) (22-52), human acetate(159899-65-7 Free base) CGRP Receptor
T76682 Galcanezumab LY 2951742 CGRP Receptor
Galcanezumab is a humanized IgG4 monoclonal antibody targeting the CGRP ligand, which binds to the ligand calcitonin gene-related peptide. Galcanezumab can be used to prevent and treat migraines or cluster headaches.
T23406 SUN B8155 SUN-B 8155 Others
calcitonin (CT) receptor agonist
T26682 Atogepant MK 8031,MK8031. Atogepant,MK-8031
Atogepant is an antagonist of calcitonin gene-related peptide receptor.
TP2044 α-CGRP(human) α-CGRP (human)
Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.
T39522 HTL22562
HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.
T16093 Telcagepant MK-0974 Others
T70248 4991W93
4991W93 is a 5HT(1B/1D) receptor partial agonist, inhibiting electrically induced plasma extravasation, blocking neurogenic plasma protein extravasation, inhibiting release of calcitonin gene-related peptide.
TP1131 β-CGRP, human TFA (101462-82-2 free base) CGRP-II (Human) (TFA),Human β-CGRP (TFA),β-CGRP, human TFA
β-CGRP,human tissue is one of the calcitonin peptide, through complex behavior of calcitonin receptor like receptor (CRLR) - and receptor activity - modifying proteins (increased), and 1 and 300 - nM CRLR IC50s/RAMP1 and...
T71246 DD04107
DD04107 is a novel inhibitor of α-calcitonin gene-related peptide (α-CGRP) exocytotic release from primary sensory neurons, selectively interacting with Synaptotagmin 1.
T26796 BI-44370
BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.
T12293 Olcegepant hydrochloride BIBN-4096 hydrochloride,BIBN4096BS hydrochloride Others
Olcegepant hydrochloride is a potent and selective non-peptidethe calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (with IC50 of 0.03 nM for human CGRP).
TP2049 CRSP-1
Endogenous central calcitonin (CT) receptor agonist that stimulates cAMP formation at a potency 350-fold greater than CT (ED50 values are 0.2 and 71 nM respectively). Displays no activity at calcitonin-gene related pepti...
T27025 Cizolirtine citrate E-4018,E4018,E 4018
Cizolirtine is a calcitonin gene-related peptide antagonist. Cizolirtine may be useful for alleviating some neuropathic somatosensory disorders, in particular cold allodynia, with a reduced risk of undesirable side effec...
T75978 β-CGRP, human TFA
Human β-CGRP TFA (β-CGRP, human TFA) is a calcitonin peptide that functions through interaction with the calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP) complex, demonstrating IC50...
TP1625 Adrenomedullin (11-50), rat
Adrenomedullin 11-50 rat is a peptide fragment of adrenomedullin that possesses systemic vasodilator activity at the level of calcitonin gene-related peptide-1 (CGRP1) receptor activation. Adrenomedullin and its peptide ...
T73703 (3R,5R,6S)-Atogepant
Atogepant ((3R,5R,6S)-MK-8031) is the enantiomer of itself and serves as a calcitonin gene-related peptide (CGRP) receptor antagonist, primarily utilized in migraine research.
T70837 Rimegepant sulfate hydrate
Rimegepant, also known as BMS-927711 and BHV-3000, is a potent, selective, competitive, and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraines. Rimegepant has shown ...
TP1232 Amylin, amide, rat Amylin (rat)
Amylin is a peptide that displays 50% homology with calcitonin gene-related peptide (CGRP), Amylin is colocalized with somatostatin in endocrine cells of the gastric fundus. In isolated mouse stomach, amylin caused a con...
TP1130 β-CGRP, human CGRP-II (Human),Human β-CGRP
β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular and nervous systems. β-CGRP contains a disulphide bridge at th...
TP1183 Amylin, amide, human DAP amide, human
Amylin, a 37-amino acid polypeptide that is structurally related to calcitonin, is secreted from the B cells of the pancreas. Amylin has anoretic effects in rats. Amylin may be responsible for the etiology of insulin res...
TP1954 PHM-27 (human)
Endogenous peptide product of human prepro-VIP and analog of porcine PHI-27; potent agonist for the human calcitonin receptor (EC50 = 11 nM). Transgenic mice expressing the human VIP/PHM 27 gene in pancreatic β-islets di...
T76678 Eptinezumab
Eptinezumab, a human monoclonal antibody, specifically binds to and blocks the calcitonin gene-related peptide (CGRP) from binding to its receptor, thus acting as a preventive treatment for migraine in adults [1].
T76262 Cagrilintide
Cagrilintide, an investigational novel long-acting acylated amylin analogue, functions as an agonist for nonselective amylin receptors (AMYR) and the calcitonin G protein-coupled receptor (CTR). It significantly reduces ...
T76680 Fremanezumab
Fremanezumab (TEV-48125), a humanized IgG2a monoclonal antibody, potently and selectively targets the calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide implicated in the central and peripheral mechanis...
T75934 AC 187 TFA
AC 187 TFA, a potent and orally active amylin receptor antagonist, exhibits an IC50 of 0.48 nM and a Ki of 0.275 nM. It demonstrates greater selectivity for the amylin receptor over calcitonin and CGRP receptors and has ...
T36555 Tyr-α-CGRP (human) (trifluoroacetate salt)
Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide . It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respecti...

Compounds

Calcitonin (salmon)
TP1040
Synonym: Calcitonin salmon,Salmon calcitonin
Target: CGRP Receptor
Calcitonin(salmon) Acetate(47931-85-1(free base))
TP1040L
Synonym: Salmon calcitonin
Target: CGRP Receptor
Calcitonin eel acetate
TP1028L
Synonym: Calcitonin eel acetate (57014-02-5 Free base),Thyrocalcitonin eel
Target: Others
Calcitonin (human)
TP2055
Synonym:
Target:
Calcitonin (salmon) (trifluoroacetate salt)
T37413
Synonym:
Target:
Calcitonin, eel
TP1028
Synonym: Thyrocalcitonin eel
Target:
Calcitonin, eel TFA (57014-02-5 free base)
TP1027
Synonym: Thyrocalcitonin eel (TFA),Calcitonin, eel TFA
Target:
Calcitonin, eel TFA
T78372
Synonym: Thyrocalcitonin eel TFA
Target:
CGRP (83-119), rat TFA
TP1200
Synonym: Calcitonin Gene Related Peptide(83-119), rat TFA
Target: Others
Calcitonin (8-32), salmon
TP1677
Synonym:
Target:
Calcitonin Gene Related Peptide (CGRP) II, rat
TP1202
Synonym: CGRP II, rat
Target:
Calcitonin Gene Related Peptide (CGRP) II, rat TFA
T76032
Synonym:
Target:
[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat
T76363
Synonym:
Target:
CGRP(83-119), rat
TP1203
Synonym: Calcitonin Gene Related Peptide (CGRP) (83-119), rat
Target:
Ubrogepant
T17194
Synonym: MK-1602
Target: CGRP Receptor
CGRP II, rat (TFA) (99889-63-1 free base)
TP1201
Synonym: Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA)
Target:
Olcegepant
T12293L
Synonym: BIBN-4096,BIBN 4096BS
Target: CGRP Receptor
Rimegepant
T4610
Synonym: BMS 927711,BMS-927711,BMS927711,BHV-3000
Target: CGRP Receptor
Vazegepant hydrochloride
T8682
Synonym: Vazegepant HCl
Target: CGRP Receptor
MK-3207 Hydrochloride
T6590
Synonym: MK-3207 HCl
Target: CGRP Receptor
CGRP (rat) acetate
TP2233L
Synonym:
Target: Others
HCGRP-(8-37) acetate
TP1134L
Synonym: HCGRP-(8-37) acetate (119911-68-1 free base)
Target: CGRP Receptor
Erenumab
T76874
Synonym: AMG-334
Target: CGRP Receptor
Adrenomedullin (AM) (22-52), human acetate
TP1257L
Synonym: Adrenomedullin (AM) (22-52), human acetate(159899-65-7 Free base)
Target: CGRP Receptor
Galcanezumab
T76682
Synonym: LY 2951742
Target: CGRP Receptor
SUN B8155
T23406
Synonym: SUN-B 8155
Target: Others
Atogepant
T26682
Synonym: MK 8031,MK8031. Atogepant,MK-8031
Target:
α-CGRP(human)
TP2044
Synonym: α-CGRP (human)
Target:
HTL22562
T39522
Synonym:
Target:
Telcagepant
T16093
Synonym: MK-0974
Target: Others
4991W93
T70248
Synonym:
Target:
β-CGRP, human TFA (101462-82-2 free base)
TP1131
Synonym: CGRP-II (Human) (TFA),Human β-CGRP (TFA),β-CGRP, human TFA
Target:
DD04107
T71246
Synonym:
Target:
BI-44370
T26796
Synonym:
Target:
Olcegepant hydrochloride
T12293
Synonym: BIBN-4096 hydrochloride,BIBN4096BS hydrochloride
Target: Others
CRSP-1
TP2049
Synonym:
Target:
Cizolirtine citrate
T27025
Synonym: E-4018,E4018,E 4018
Target:
β-CGRP, human TFA
T75978
Synonym:
Target:
Adrenomedullin (11-50), rat
TP1625
Synonym:
Target:
(3R,5R,6S)-Atogepant
T73703
Synonym:
Target:
Rimegepant sulfate hydrate
T70837
Synonym:
Target:
Amylin, amide, rat
TP1232
Synonym: Amylin (rat)
Target:
β-CGRP, human
TP1130
Synonym: CGRP-II (Human),Human β-CGRP
Target:
Amylin, amide, human
TP1183
Synonym: DAP amide, human
Target:
PHM-27 (human)
TP1954
Synonym:
Target:
Eptinezumab
T76678
Synonym:
Target:
Cagrilintide
T76262
Synonym:
Target:
Fremanezumab
T76680
Synonym:
Target:
AC 187 TFA
T75934
Synonym:
Target:
Tyr-α-CGRP (human) (trifluoroacetate salt)
T36555
Synonym:
Target:
1 2
カタログ番号 製品名 別名 ターゲット
TP2167 β-CGRP, human acetate β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate CGRP Receptor
β-CGRP, human acetate is one of calcitonin peptides and acts via the complex of receptor-activity-modifying protein (RAMP) and calcitonin-receptor-like receptor (CRLR) (IC50s: 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP...
T15157 Dodecanoylcarnitine Lauroylcarnitine Endogenous Metabolite
Dodecanoylcarnitine ((-)-Lauroylcarnitine) has been associated with disturbances in fatty acid oxidation, and the use of Dodecanoylcarnitine resulted in an increase in the permeability of salmon calcitonin.
T21581L AC 187 Acetate AC 187 Acetate (151804-77-2 Free base) Amylin Receptor
AC 187 Acetate is a potent antagonist of amylin receptor .AC 187 shows more selective for amylin receptor than calcitonin and CGRP receptors.

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-00085 Calcitonin receptor Protein, Human, Recombinant (aa 1-153, hFc) Human HEK293 Cells
Calcitonin receptor Protein, Human, Recombinant (aa 1-153, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.1 kDa and the accession number is P30988-2.
TMPY-00317 Calcitonin receptor Protein, Human, Recombinant (aa 25-154, hFc) Human HEK293 Cells
Calcitonin receptor Protein, Human, Recombinant (aa 25-154, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.9 kDa and the accession number is P30988-1.
TMPK-00678 CALCA/CGRP Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 a...
TMPY-03963 CALCB Protein, Human, Recombinant (mFc) Human HEK293 Cells
CALCB, also known as CGPR and calcitonin 2, belongs to the calcitonin family. CALCB is a calcitonin (CT) peptide which may play a role in the mediation of human inflammatory diseases. It is highly expressed in the skin, ...
TMPH-01025 CALCA Protein, Human, Recombinant (GST) Human E. coli
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevate...
TMPY-04120 Procalcitonin/CALCA Protein, Human, Recombinant (mFc) Human HEK293 Cells
Procalcitonin/CALCA Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 39.2 kDa and the accession number is P01258-1.
TMPY-00066 Procalcitonin/CALCA Protein, Human, Recombinant (His) Human HEK293 Cells
Procalcitonin/CALCA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.2 kDa and the accession number is P01258-1.
TMPY-03280 RAMP3 Protein, Human, Recombinant (hFc) Human HEK293 Cells
RAMP3 belongs to the RAMP family. Members of this family are single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs have a wide biological distribution; high concent...
TMPY-02839 Adrenomedullin Protein, Human, Recombinant (hFc) Human HEK293 Cells
Adrenomedullin consists of 52 amino acids and is a member of the adrenomedullin family. It s a a hypotensive peptide and has 1 intramolecular disulfide bond. It seems that adrenomedullin has a slight homology with the ca...
TMPY-00371 STC1 Protein, Human, Recombinant (His) Human HEK293 Cells
Stanniocalcin-1 (STC1) is a paracrine factor associated with inflammation and carcinogenesis. STC1 is a secreted glycoprotein hormone and involved in various types of human malignancies. Stanniocalcin-1 (STC1), which has...
TMPH-01282 ELAVL4 Protein, Human, Recombinant (His & Myc & SUMO) Human E. coli
RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in th...