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Search Results for " Smad1/5 "

ターゲット

3

阻害剤

1

天然化合物

17

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T1943 ML347 LDN 193719 ALK , TGF-beta/Smad
ML347 (LDN 193719)(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the selectivity for ALK2 is >300-fold than ALK3.
T16904 Smurf1-IN-A01 A01 Others
Smurf1-IN-A01 (A01) is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM). It increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.
T76863 Elezanumab AE12-1Y-QL,ABT-555 TGF-beta/Smad
Elezanumab(ABT-555) is a potent human anti-RGMa monoclonal antibody.Elezanumab exerts its inhibitory effect on RGMa-mediated BMP signaling through the SMAD1/5/8 pathway, with an IC50 of approximately 97 pM.Elezanumab pro...
カタログ番号 製品名 別名 ターゲット
T3924 Astragaloside II Astrasieversianin VIII TGF-beta/Smad
Astragaloside II (Astrasieversianin VIII) is an effective MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Astragaloside II also induces osteogenic activities, differentiation, ...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-04018 LRG1 Protein, Human, Recombinant Human HEK293
LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell...
TMPY-03966 LRG1 Protein, Human, Recombinant (His) Human HEK293
LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell...
TMPH-01018 BMP-6 Protein, Human, Recombinant (His) Human E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes including cartilage and bone formation. Plays also an important role in the regulation of iron metabolism by acting as ...
TMPJ-00966 GDF-5 Protein, Human, Recombinant Human E. coli
Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor...
TMPY-03965 LRG1 Protein, Human, Recombinant (hFc) Human HEK293
LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell...
TMPH-01019 BMP-7 Protein, Human, Recombinant (GST) Human E. coli
Growth factor of the TGF-beta superfamily that plays important role in various biological processes, including embryogenesis, hematopoiesis, neurogenesis and skeletal morphogenesis. Initiates the canonical BMP signaling ...
TMPH-00228 BMP-4 Protein, Bovine, Recombinant (GST) Bovine E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu...
TMPH-01014 BMP-2 Protein, Human, Recombinant (His) Human E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cardiogenesis, neurogenesis, and osteogenesis. Induces cartilage and bone formation. Initiates the canonical...
TMPH-01017 BMP-4 Protein, Human, Recombinant (His) Human E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu...
TMPY-05308 CD45 Protein, Human, Recombinant (aa 1-529, His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-00854 ETS1 Protein, Human, Recombinant (His) Human E. coli
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or ...
TMPY-05387 SLAMF7 Protein, Human, Recombinant (hFc) Human HEK293
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPY-05498 SR-BI/SCARB1 Protein, Human, Recombinant (hFc) Human HEK293
Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPY-05547 SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated Human HEK293
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPY-04318 GRIK2 Protein, Human, Recombinant (hFc) Human HEK293
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar...
TMPK-01363 SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
TMPK-01357 SIRP alpha V5 Protein, Human, Recombinant (His & Avi) Human HEK293
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
LRG1 Protein, Human, Recombinant
TMPY-04018
Species: Human
Expression System: HEK293
LRG1 Protein, Human, Recombinant (His)
TMPY-03966
Species: Human
Expression System: HEK293
BMP-6 Protein, Human, Recombinant (His)
TMPH-01018
Species: Human
Expression System: E. coli
GDF-5 Protein, Human, Recombinant
TMPJ-00966
Species: Human
Expression System: E. coli
LRG1 Protein, Human, Recombinant (hFc)
TMPY-03965
Species: Human
Expression System: HEK293
BMP-7 Protein, Human, Recombinant (GST)
TMPH-01019
Species: Human
Expression System: E. coli
BMP-4 Protein, Bovine, Recombinant (GST)
TMPH-00228
Species: Bovine
Expression System: E. coli
BMP-2 Protein, Human, Recombinant (His)
TMPH-01014
Species: Human
Expression System: E. coli
BMP-4 Protein, Human, Recombinant (His)
TMPH-01017
Species: Human
Expression System: E. coli
CD45 Protein, Human, Recombinant (aa 1-529, His)
TMPY-05308
Species: Human
Expression System: HEK293
ETS1 Protein, Human, Recombinant (His)
TMPJ-00854
Species: Human
Expression System: E. coli
SLAMF7 Protein, Human, Recombinant (hFc)
TMPY-05387
Species: Human
Expression System: HEK293
SR-BI/SCARB1 Protein, Human, Recombinant (hFc)
TMPY-05498
Species: Human
Expression System: HEK293
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05547
Species: Human
Expression System: HEK293
GRIK2 Protein, Human, Recombinant (hFc)
TMPY-04318
Species: Human
Expression System: HEK293
SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-01363
Species: Human
Expression System: HEK293
SIRP alpha V5 Protein, Human, Recombinant (His & Avi)
TMPK-01357
Species: Human
Expression System: HEK293