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Search Results for " TGFB1 "

ターゲット

2

阻害剤

14

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T80562 Nisevokitug NIS-793 TGF-beta/Smad
Nisevokitug (NIS-793) is an IgG2λ human monoclonal antibody that targets TGF-β (TGFB1/TGFB2). It is produced in CHO-K1 cells [1].
T77000 Cirevetmab
Cirevetmab (ZTS-00521426), a caninized monoclonal antibody targeting Canis lupus familiaris TGFB1, is classified as an immunoglobulin G2-kappa. It functions as an immunomodulator [1].

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-00249 TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated Human HEK293 Cells
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-...
TMPJ-00772 Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 35-45 KDa and the accession number is P04202.
TMPJ-00622 Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 11 and 35-45 KDa and the accession number is F7HCV5.
TMPJ-00250 LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activ...
TMPJ-00771 TGF beta 1 Protein, Mouse/Rat, Recombinant Mouse,Rat HEK293 Cells
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differen...
TMPH-02748 KCP Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways. KCP Protein, Mouse, Recombinant (His & Myc) is expressed in E....
TMPH-02803 NRROS Protein, Mouse, Recombinant (His) Mouse E. coli
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi...
TMPH-02594 MMP-13 Protein, Mouse, Recombinant (His) Mouse E. coli
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the hig...
TMPJ-01093 HYAL1 Protein, Human, Recombinant (His) Human HEK293 Cells
Hyaluronidase-1 (HYAL1) is a secreted lysosomal hyaluronidase that belongs to the glycosyl hydrolase 56 family. HYAL1 contains one EGF-like domain and is highly expressed in the liver, kidney, and heart, but it is weakly...
TMPH-02055 RBPMS Protein, Human, Recombinant (His & Myc) Human E. coli
Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 an...
TMPJ-01085 DPT Protein, Human, Recombinant (hFc & His) Human HEK293 Cells
Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal ...
TMPJ-01369 DPT Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Dermatopontin is a widely expressed noncollagenous protein component of the extracellular matrix. It is a 22 kDa molecule that is tyrosine sulfated but not glycosylated. Dermatopontin is down regulated in fibrotic growth...
TMPH-01269 SMURF2 Protein, Human, Recombinant (His) Human E. coli
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD7 to trigger SMA...
TMPH-03764 YAP1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor su...