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T13954 |
UNC6852
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Histone Methyltransferase
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Ligands for Target Protein for PROTAC
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UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC. |
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T17649 |
Boc-GABA-OH
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Others
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PROTAC Linker
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Boc-GABA-OH serves as a PROTAC linker essential for synthesizing UNC6852, an EED-targeted PROTAC[1]. |
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T18664 |
(S,R,S)-AHPC-C3-NH2
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VH032-C3-NH2 |
Others
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(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized conjugate consisting of an E3 ligase ligand-linker and the VH032 based VHL ligand, which is commonly used in PROTAC technology. This compound serves as a key component ... |
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T17931 |
EED226-COOH
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Others
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EED226-COOH, derived from EED226, serves as a ligand targeting the EED protein for PROTAC applications. It attaches to a VHL ligand through a linker, culminating in the formation of UNC6852, which specifically degrades P... |
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T18663 |
(S,R,S)-AHPC-C3-NH2 TFA (2361119-88-0 free base)
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(S,R,S)-AHPC-C3-NH2 TFA,VH032-C3-NH2 TFA |
Others
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(S,R,S)-AHPC-C3-NH2 TFA (VH032-C3-NH2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the sy... |
