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Search Results for " XPO1 "

5

阻害剤

7

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T63623 XPO1-IN-1
XPO1-IN-1 is an orally active XPO1 inhibitor capable of acting on MM.1S cells (IC50: 24 nM). XPO1-IN-1 effectively induces cell cycle arrest and apoptosis. XPO1-IN-1 exhibits good metabolic stability and pharmacokinetic ...
T24269 KPT-251 KPT251 Others
KPT-251 is a selective nuclear export inhibitor.
T15735 Leptomycin B CI 940,LMB CRM1 , Antibiotic , Antifungal
Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a ...
T11766L Eltanexor ONO-7706,KPT-8602,ATG-016 Others
Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes ...
T6123 Verdinexor KPT-335 CRM1
Verdinexor (KPT-335) (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-02733 IFI27L2A Protein, Mouse, Recombinant (His) Mouse E. coli
May be involved in the interferon-induced negative regulation of the transcriptional activity of NR4A1, NR4A2 and NR4A3 through the enhancement of XPO1-mediated nuclear export of these nuclear receptors. Through the regu...
TMPH-02353 Influenza A H1N1 (strain A/Fort Warren/1/1950) Nucleoprotein/NP Protein (His & SUMO) H1N1 E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l...
TMPH-02355 Influenza A H3N2 (strain A/Port Chalmers/1/1973) Nucleoprotein/NP Protein (His & SUMO) H3N2 E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l...
TMPH-02350 Influenza A H3N2 (strain A/Shanghai/16/1989) Nucleoprotein/NP Protein (His) H3N2 E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l...
TMPH-02354 Influenza A H1N1 (strain A/New Jersey/8/1976) Nucleoprotein/NP Protein (His & SUMO) H1N1 E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l...
TMPH-02351 Influenza A H3N2 (strain A/Beijing/353/1989) Nucleoprotein/NP Protein (His & SUMO) H3N2 E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l...
TMPH-02352 Influenza A H3N2 (strain A/Kitakyushu/159/1993) Nucleoprotein/NP Protein (His) H3N2 E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l...