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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T63623 | XPO1-IN-1 | ||
XPO1-IN-1 is an orally active XPO1 inhibitor capable of acting on MM.1S cells (IC50: 24 nM). XPO1-IN-1 effectively induces cell cycle arrest and apoptosis. XPO1-IN-1 exhibits good metabolic stability and pharmacokinetic ... | |||
T24269 | KPT-251 | KPT251 | Others |
KPT-251 is a selective nuclear export inhibitor. | |||
T15735 | Leptomycin B | CI 940,LMB | CRM1 , Antibiotic , Antifungal |
Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a ... | |||
T11766L | Eltanexor | ONO-7706,KPT-8602,ATG-016 | Others |
Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes ... | |||
T6123 | Verdinexor | KPT-335 | CRM1 |
Verdinexor (KPT-335) (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable. |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPH-02733 | IFI27L2A Protein, Mouse, Recombinant (His) | Mouse | E. coli |
May be involved in the interferon-induced negative regulation of the transcriptional activity of NR4A1, NR4A2 and NR4A3 through the enhancement of XPO1-mediated nuclear export of these nuclear receptors. Through the regu... | |||
TMPH-02353 | Influenza A H1N1 (strain A/Fort Warren/1/1950) Nucleoprotein/NP Protein (His & SUMO) | H1N1 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l... | |||
TMPH-02355 | Influenza A H3N2 (strain A/Port Chalmers/1/1973) Nucleoprotein/NP Protein (His & SUMO) | H3N2 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l... | |||
TMPH-02350 | Influenza A H3N2 (strain A/Shanghai/16/1989) Nucleoprotein/NP Protein (His) | H3N2 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l... | |||
TMPH-02354 | Influenza A H1N1 (strain A/New Jersey/8/1976) Nucleoprotein/NP Protein (His & SUMO) | H1N1 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l... | |||
TMPH-02351 | Influenza A H3N2 (strain A/Beijing/353/1989) Nucleoprotein/NP Protein (His & SUMO) | H3N2 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l... | |||
TMPH-02352 | Influenza A H3N2 (strain A/Kitakyushu/159/1993) Nucleoprotein/NP Protein (His) | H3N2 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l... |