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カタログ番号 | 製品名 | 別名 | ターゲット |
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T15058 | DBCO-amine | ||
DBCO-amine is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis[1]. | |||
T22334 | FMOC-3VVD-OH | Others | |
FMOC-3VVD-OH is an active chemical. | |||
T17389 | AMAS | Others | |
AMAS is a non-claevable heterobifunctional crosslinker with NHS ester and maleimide groups that enables covalent conjugation of amine- and sulfhydryl-containing molecules. | |||
T4346 | SPDB | Others | |
SPDB is a small fragment linked to DM4 conjugates. It conjugates to antibodies utilizing disulfide linkers: anti-EGFR-SPDB-DM4 has been widely used. | |||
T16218 | N-Boc-PEG5-bromide | Others , PROTAC Linker | |
N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T15179 | DTSSP Crosslinker | Others | |
DTSSP Crosslinker is a cleavable ADC linker and can be used to synthesize antibody-drug conjugates (ADCs). | |||
T15176 | DSS Crosslinker | Others | |
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters a... | |||
T18723 | Succinic anhydride | Others | |
Succinic anhydride is a cyclic anhydride. Succinic anhydride acts as a nonclaevable ADC linker. Succinic anhydride can react with compound 4 to link the prodrug to an amine or hydroxy 1 group of a targeting polypeptide. | |||
T22278 | BOC-Dap-NE | Others | |
Boc-Dap-NE used in the synthesis of antibody-drug conjugates (ADCs).It is a cleavable ADC linker | |||
T18479 | NH-bis(C1-Boc) | Others | |
NH-bis(C1-Boc)is a uncleavable linker. NH-bis can be used for antibody-drug conjugates (ADC). | |||
T15171 | DSG Crosslinker | Others | |
DSG Crosslinker is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. | |||
T15175 | DSP Crosslinker | Others | |
DSP Crosslinker is a cleavable ADC linker, used in antibody-drug conjugates (ADCs) synthesis[1]. | |||
T18868 | Val-Cit | Others | |
Val-Cit is a cleavable ADC linker. Val-Cit is used in the synthesis of antibody-drug conjugates (ADCs). | |||
T8924 | MFCD28987368 | Others | |
MFCD28987368 is a degradable ADC linker that can be used in the synthesis of antibody coupled drugs (ADCs). | |||
T17691 | Boc-Val-Cit-OH | Others | |
Boc-Val-Cit-OH is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. | |||
T6741 | SPDP | SPDP Crosslinker | Others |
SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could ... | |||
T17372 | Ald-Ph-NHS ester | Others | |
Ald-Ph-NHS ester is a non-cleavable linker used in antibody-drug-conjugation (ADC). | |||
T17693 | Boc-Val-Cit-PAB | Others | |
Boc-Val-Cit-PAB is a cleavable ADC linker. Boc-Val-Cit-PAB used in the synthesis of antibody-drug conjugates (ADCs). | |||
T17952 | Fmoc-Gly-Gly-OH | Others | |
Fmoc-Gly-Gly-OH is a cleavable ADC linker. Fmoc-Gly-Gly-OH can be used in the synthesis of antibody-drug conjugates (ADCs). | |||
T4678 | Fmoc-Val-Cit-PAB | Others | |
Fmoc-Val-Cit-PAB is a linker for antibody-drug-conjugation (ADC). | |||
T18308 | MC-Gly-Gly-Phe | ||
MC-Gly-Gly-Phe is a cleavable linker. MC-Gly-Gly-Phe can be used for antibody-drug conjugates (ADC). | |||
T17213 | Val-cit-PAB-OH | Others | |
Val-cit-PAB-OH is an ADC linker that is cleavable. | |||
T7767 | FMoc-Val-Cit-PAB-PNP | Others | |
Fmoc-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). | |||
T17953 | Fmoc-Gly-Gly-Phe-OtBu | Others | |
Fmoc-Gly-Gly-Phe-OtBu is a cleavable ADC linker. Fmoc-Gly-Gly-Phe-OtBu can be used in the synthesis of antibody-drug conjugates (ADCs). | |||
T18540 | Phe-Lys(Trt)-PAB | Others | |
Phe-Lys(Trt)-PAB is a cathepsin-cleavable linker utilized in the development of antibody-drug conjugates (ADCs)[1], serving as a crucial component for facilitating the release of therapeutic agents within targeted cells. | |||
T18321 | Mc-Val-Cit-PAB-Cl | Others | |
Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC5... | |||
T16225 | N-Hydroxysulfosuccinimide sodium | ||
N-Hydroxysulfosuccinimide sodium is a non-cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. | |||
T18728 | Sulfo-SMCC sodium | Others | |
Sulfo-SMCC sodium, a widely utilized non-cleavable, hetero-bifunctional crosslinker for antibody-drug conjugates (ADCs), features both N-hydroxysuccinimide (NHS) ester and maleimide groups. These functionalities enable i... | |||
T38953 | Azido-C6-OH | Others | |
Azido-C6-OH is a cleavable ADC linker used to synthesize antibody-drug conjugates (ADCs). | |||
T17692 | Boc-Val-Cit-PAB-PNP | Others | |
Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. | |||
T18318 | MC-Val-Ala-PAB-PNP | Others | |
MC-Val-Ala-PAB-PNP is a cleavable ADC linker. MC-Val-Ala-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs). | |||
T41312 | Fmoc-Lys-OH hydrochloride | PROTAC Linker | |
Fmoc-Lys-OH hydrochloride is a alkyl-chain-based PROTAC linker. Fmoc-Lys-OH hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | |||
T9783 | Boc-C16-COOH | PROTAC Linker | |
Boc-C16-COOH is a alkyl-chain-based PROTAC linker. Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | |||
T14635 | Bis-PEG3-NHS ester | Others | |
Bis-PEG3-NHS ester is a nonclaevable 3-unit PEG linker used in antibody-drug-conjugation (ADC). | |||
T18467 | N3-C4-NHS ester | Others | |
N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | |||
T9282 | DBCO-C3-Acid | DBCO-ACID | Others |
DBCO acid 2 is a Click Chemistry intermidate used for antibody-drug conjugates. | |||
T17946 | Fmoc-Ala-Ala-Asn(Trt)-OH | Others | |
Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable linker vital in ADC synthesis. Fmoc-Ala-Ala-Asn(Trt)-OH joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled... | |||
T17679 | Boc-NH-PEG4-CH2CH2NH2 | Others , PROTAC Linker | |
Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T8667 | MC-Gly-Gly-Phe-Gly | DSN28369 | Others |
MC-Gly-Gly-Phe-Gly (DSN28369) is a heterobifunctional linker, and useful to make antibody drug conjuate (ADC). | |||
T18408 | N-Butanoyl-L-homoserine lactone | N-Butyryl-L-homoserine lactone,C4-HSL | Antibacterial |
N-Butanoyl-L-homoserine lactone is a degradable ADClinker used in the synthesis of antibody-coupled drugs. It can be used in antimicrobial biofilms and has antimicrobial activity. Its aptamer inhibits Pseudomonas aerugin... | |||
T9785 | 20-(tert-Butoxy)-20-oxoicosanoic acid | PROTAC Linker | |
20-(tert-Butoxy)-20-oxoicosanoic acid is a alkyl-chain-based PROTAC linker. 20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | |||
T4289 | Mc-Val-Ala-PAB | Mc-Val-Ala-PAB | Others , AChR |
Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC). | |||
T18529 | PDEC-NB | 4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate | Others |
PDEC-NB (4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate) is a disulfide cleavable linker. PDEC-NB can be used for the antibody-drug conjugate (ADC). | |||
T16605 | Propargyl-PEG3-acid | PROTAC Linker | |
Propargyl-PEG3-acid is a non-cleavable (3-unit PEG) ADC linker. Propargyl-PEG3-acid is also a PEG-based PROTAC linker used to synthesize 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA and Propargyl-PEG3-acid[1]. | |||
T17950 | Fmoc-Asp-NH2 | Others | |
Fmoc-Asp-NH2 is a cleavable ADC linker. Fmoc-Asp-NH2 can be used in the synthesis of antibody-drug conjugates (ADCs). | |||
T17654 | Boc-NH-C6-Br | Others | |
Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC)[1]. | |||
T15976 | Mal-PEG1-NHS ester | Others , PROTAC Linker | |
Mal-PEG1-NHS ester is a cleavable and PEG-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It also is PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | |||
T17842 | DOTA-NHS-ester | Others | |
DOTA-NHS-ester is a linker of affibody molecules for small animal PET, SPECT and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for tumor detection. | |||
T14833L | BS3 Crosslinker disodium | Others | |
BS3 Crosslinker disodium is a non-cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. | |||
T18031 | Hydroxy-PEG10-acid | HO-PEG10-CH2CH2COOH | Others , PROTAC Linker |
Hydroxy-PEG10-acid (HO-PEG10-CH2CH2COOH) is a PEG-based PROTAC linker that can be used to synthesize PROTACs[1]. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T9784 | Docosanedioic acid | PROTAC Linker | |
BEHENIC ACID is a alkyl-chain-based PROTAC linker. BEHENIC ACID is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | |||
T4820 | Maleimide | 2,5-Pyrroledione | Others |
Maleimide (2,5-Pyrroledione) (2,5-Pyrroledone) is a new nanoparticle surface functional group which favors easy conjugation with cell penetration peptides. The conjugation is enabled via click chemistry to preserve its b... | |||
T39562 | γ-Amanitin | ||
γ-Amanitin, an ADC (antibody-drug conjugate) cytotoxin isolated from mushrooms, inhibits RNA polymerase II, disrupting mRNA synthesis. It exhibits effects akin to those of α-Amanitin and β-Amanitin. | |||
T73915 | Luisol A | ||
Luisol A, an aromatic tetraol and anthraquinone antibiotic analog, serves as a significant metabolite produced by an estuarine marine actinomycete from the genus Streptomyces. Additionally, it functions as an ADC (Antibo... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPK-00618 | FcRH5/FcRL5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),... | |||
TMPK-01039 | FcRH5/FcRL5 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),... | |||
TMPK-01145 | FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),... | |||
TMPK-00619 | FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),... | |||
TMPJ-01028 | Claudin-18.2 Protein, Human, Recombinant (Twin strep & Flag) | Human | HEK293 Cells |
Claudin-18 (CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial ... | |||
TMPJ-00751 | IgG4 hFc Protein, Human, Recombinant (aa 99-326) | Human | HEK293 Cells |
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma ... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L2170 | Immuno-Oncology Compound Library | 449 compounds | |
A unique collection of 449 compounds acting on immune-oncology therapeutic targets can be used for high throughput and high content screening; |