endoribonuclease | TargetMol

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Search Results for " endoribonuclease "

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阻害剤

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T9564	IRE1α kinase-IN-1		IRE1
	IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosph...		IRE1
T11669	IR415		HBV
			HBV
T24098	GP17	GP-17,GP 17
	GP17 is a type II kinase inhibitor of the IRE1α endoribonuclease that acts by targeting the ATP-binding pocket of IRE1α.
T24099	GP29	GP-29,GP 29
	GP29 is a Type II kinase inhibitor of the IRE1α endoribonuclease that acts by targeting the ATP-binding pocket of IRE1α.
T63951	ZINC000104379474
	ZINC000104379474 is a compound that targets SARS-CoV-2 endoribonuclease.
T38234	HCoV-229E-IN-1
	HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, demonstrating efficacy with an EC50 value of 0.65 μM in MTS cells and 0.6 μM in CPE cells[1].

Compounds

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-00574	Adenylate cyclase Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Catalyzes the formation of the second messenger cAMP from ATP. Its transcript is probably degraded by endoribonuclease LS (rnlA), decreasing cAMP levels and the negative regulator Crp-cAMP, which then induces its own tra...
TMPH-00730	RpoS Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and...
TMPH-03565	MazF Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	Toxic component of a type II toxin-antitoxin (TA) system. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. It cuts between the f...
TMPH-00731	RpoS Protein, E. coli, Recombinant	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and...
TMPH-03582	MazF Protein, S. epidermidis, Recombinant (His)	Staphylococcus epidermidis	E. coli
	Toxic component of a type II toxin-antitoxin (TA) system. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. It cuts between the f...
TMPJ-01007	HRSP12 Protein, Human, Recombinant (His)	Human	E. coli
	Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA...