4
3
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T7100 | PLX5622 | PLX-5622 | c-Fms , CSF-1R |
PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor. | |||
T68474 | RWJ-58643 HCl | ||
RWJ 58643 is a reversible beta-tryptase and trypsin inhibitor. Low-dose RWJ-58643 (100 microg) and budesonide (200 microg) significantly reduced symptoms, eosinophils and levels of IL-5 following NAC. However, higher dos... | |||
T12505 | PLX5622 hemifumarate | c-Fms | |
PLX5622 hemifumarate is a highly selective brain penetrant and orally active CSF1R inhibitor with an IC 50 of 0.016 μM and Ki of 5.9 nM. PLX5622 hemifumarate allows for extended and specific microglial elimination, prece... | |||
T70527 | DAT-230 | ||
DAT-230 is a promising microtubule inhibitor that has great potential for the treatment of fibrosarcoma in vitro and in vivo. DAT-230 exhibited potent anti-proliferative activity against various cancer cells. DAT-230 -tr... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-02300 | BIN1 Protein, Human, Recombinant (His) | Human | E. coli |
Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicat... | |||
TMPY-03269 | Prolyl Endopeptidase Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Prolyl endopeptidase, also known as PREP, belongs to a distinct class of serine peptidases. It is a large cytosolic enzyme which was first described in the cytosol of rabbit brain as an oligopeptidase. Prolyl endopeptida... | |||
TMPJ-00304 | ALK-1 Protein, Mouse, Recombinant (hFc) | Mouse | Human Cells |
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angi... |