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ターゲット

4

阻害剤

3

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T7100 PLX5622 PLX-5622 c-Fms , CSF-1R
PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor.
T68474 RWJ-58643 HCl
RWJ 58643 is a reversible beta-tryptase and trypsin inhibitor. Low-dose RWJ-58643 (100 microg) and budesonide (200 microg) significantly reduced symptoms, eosinophils and levels of IL-5 following NAC. However, higher dos...
T12505 PLX5622 hemifumarate c-Fms
PLX5622 hemifumarate is a highly selective brain penetrant and orally active CSF1R inhibitor with an IC 50 of 0.016 μM and Ki of 5.9 nM. PLX5622 hemifumarate allows for extended and specific microglial elimination, prece...
T70527 DAT-230
DAT-230 is a promising microtubule inhibitor that has great potential for the treatment of fibrosarcoma in vitro and in vivo. DAT-230 exhibited potent anti-proliferative activity against various cancer cells. DAT-230 -tr...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-02300 BIN1 Protein, Human, Recombinant (His) Human E. coli
Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicat...
TMPY-03269 Prolyl Endopeptidase Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Prolyl endopeptidase, also known as PREP, belongs to a distinct class of serine peptidases. It is a large cytosolic enzyme which was first described in the cytosol of rabbit brain as an oligopeptidase. Prolyl endopeptida...
TMPJ-00304 ALK-1 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angi...