|
T4616 |
Metoclopramide
|
5-Chloro-2-methoxyprocainamide |
Dopamine Receptor
,
5-HT Receptor
|
|
Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is ... |
|
T1069 |
Metoclopramide hydrochloride
|
Maxolon,Metoclopramide HCl |
Dopamine Receptor
,
5-HT Receptor
,
AChR
|
|
Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic. |
|
T8385 |
Metoclopramide hydrochloride hydrate
|
Metoclopramide monohydrochloride monohydrate |
Dopamine Receptor
,
5-HT Receptor
|
|
Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug used for digestive dysfunction. It acts as an anti-emetic |
|
T1528 |
Azasetron hydrochloride
|
Y-25130 hydrochloride,Y-25130 HCl,Azasetron HCl |
5-HT Receptor
|
|
Azasetron hydrochloride (Y-25130 HCl) is a 5-HT3 receptor antagonist which is used as an anti-emetic. |
|
T11326 |
Frovatriptan succinate hydrate
|
Frovelan,Frova |
5-HT Receptor
|
|
Frovatriptan succinate hydrate (Frova) is effective in treating the full spectrum of migraine including the associated symptoms of nausea, vomiting, photophobia, and phonophobia. Frovatriptan succinate hydrate can also b... |
|
T1478 |
Ondansetron hydrochloride dihydrate
|
SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride |
5-HT Receptor
|
|
Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, a... |
|
T1790 |
Fosaprepitant dimeglumine
|
L785298,MK-0517,Fosaprepitant dimeglumine salt |
Neurokinin receptor
|
|
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion... |
|
T28187 |
Nonabine
|
|
|
|
Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy. |
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T22313 |
Dolasetron Mesylate
|
Anzemet hydrate,MDL-73147EF |
Others
,
5-HT Receptor
|
|
Dolasetron Mesylate (MDL-73147EF) is an antagonist of the 5-HT3 receptor and can be used in research on the treatment of vomiting and nausea following chemotherapy. |
|
T68068 |
Ezlopitant
|
CJ 11974,CJ-11974,CJ11974 |
Neurokinin receptor
|
|
Ezlopitant (CJ-11974) is a small molecule neurokinin-1-receptor (NK1) antagonist used to treat nausea, vomiting and pain. |
|
T6616 |
Ondansetron hydrochloride
|
SN 307,Ondansetron HCl,Emeset,GR 38032 HCl,NSC 665799,Zofran |
5-HT Receptor
|
|
Ondansetron hydrochloride (Zofran) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy. |
|
T13329L |
Vofopitant dihydrochloride
|
GR 205171A,Vofopitant 2HCl |
Neurokinin receptor
|
|
Vofopitant dihydrochloride (GR 205171A) is an orally available, selective tachykinin NK1 receptor antagonist that inhibits [3H]SP binding to NK1 with pKi values of 9.5 and 10.6, respectively.Vofopitant dihydrochloride is... |
|
T2574 |
Alizapride hydrochloride
|
Alizapride HCl |
Dopamine Receptor
|
|
Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting. |
|
T6426 |
Buclizine dihydrochloride
|
Longifene,Buclina,Buclizine HCl,UCB-4445 |
5-HT Receptor
,
AChR
,
Histamine Receptor
|
|
Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine dihydrochloride binds to and ... |
|
T7569 |
Clebopride malate
|
|
Dopamine Receptor
|
|
Clebopride malate is a dopamine antagonist drug Used to treat functional gastrointestinal disorders such as nausea or vomiting. |
|
T68068L |
(R)-CJ 11974
|
|
Neurokinin receptor
|
|
(R)-CJ 11974 is a novel non-peptide neurokinin NK1 substance P receptor antagonist with potential analgesic activity that can be used to study chemotherapy-induced vomiting. |
|
T4568 |
Dolasetron
|
MDL-73147 |
5-HT Receptor
|
|
Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist. Dolasetron is used to treat nausea and vomiting following chemotherapy. |
|
T0385 |
Prochlorperazine Maleate
|
Prochlorperazin,Capazine,Prochlorperazine dimaleate salt,Stemetil,Compazine |
Dopamine Receptor
|
|
Prochlorperazine Maleate (Capazine) is a phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. |
|
T5009 |
Trimethobenzamide hydrochloride
|
Ro 2-9578,Tribenzagan Hydrochloride |
Dopamine Receptor
,
Influenza Virus
|
|
Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting. |
|
T3716 |
Rolapitant
|
SCH619734 |
Neurokinin receptor
|
|
Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ... |
|
T67956 |
Litoxetine
|
|
5-HT Receptor
|
|
Litoxetine is a selective 5-HT uptake inhibitor and is a 5-HT3 receptor antagonist. Litoxetine acts as an antidepressant and has shown antiemetic properties in ferrets. Litoxetine (1 and 10 mg/kg i.v.) dose-dependently r... |
|
T2589 |
Dolasetron Mesylate hydrate
|
Dalasetron Mesylate Hydrate |
5-HT Receptor
|
|
Dolasetron Mesylate hydrate (Dalasetron Mesylate Hydrate) , a selective serotonin receptor antagonist, competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radioth... |
|
T0976 |
Propoxur
|
Aprocarb,Propoxure,Baygon |
AChR
,
Antifungal
|
|
Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red b... |
|
T0944 |
Levamisole hydrochloride
|
(-)-Tetramisole hydrochloride |
Phospholipase
,
AChR
,
Parasite
,
HSV
|
|
Levamisole hydrochloride ((-)-Tetramisole hydrochloride) is an antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemo... |
|
T0082 |
Domperidone
|
R33812 |
Dopamine Receptor
|
|
Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger z... |
|
T4562 |
Ramosetron
|
|
5-HT Receptor
|
|
Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondanse... |
|
T10515 |
Anti-Heart Failure Agent 1
|
|
Others
|
|
Anti-Heart Failure Agent 1 is an orally available compound suitable for the treatment of heart failure without inducing vomiting, nausea, and restlessness. |
|
T22393 |
Palonosetron
|
RS25259,RS 25259 197 |
5-HT Receptor
|
|
Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). |
|
T69012 |
Cinnarizine clofibrate
|
|
|
|
Cinnarizine clofibrate is a calcium channel protein inhibitor as well as an antihistamine channel blocker. The compound is a drug derivative of piperazine. Cinnarizine is used for the control of vomiting due to motion si... |
|
T26079 |
RI 61
|
RI-61,Pro-his-pro-phe-his-leu-phe-val-phe,RI61 |
|
|
RI 61 (sumatriptan succinate) is utilized in the therapy of migraine, cluster headaches, new daily persistent headache, and cyclic vomiting syndrome. |
|
T15743 |
Levomepromazine
|
Methotrimeprazine |
Others
|
|
Methotrimeprazine is an orally available neuroleptic agent. It is commonly used to relieve nausea and vomiting in palliative care settings. Levomepromazine has antagonist actions at multiple neurotransmitter receptor sit... |
|
T16433 |
Pancopride
|
LAS 30451 |
5-HT Receptor
|
|
Pancopride（LAS 30451） is a novel, orally available, long-acting, selective 5-HT3 receptor antagonist that blocks nitrogen mustard and dacarbazine-induced vomiting. |
|
T33583 |
Naldemedine
|
S-297995,S297995,Naldemedine,S 297995,S297,995,S 297,995,S297,995;Naldemedine,S-297,995 |
|
|
Naldemedine (S 297995) is a peripheral selective μ-opioid receptor antagonist being developed by Shionogi for the treatment of opioid-induced adverse reactions, including constipation, nausea, and vomiting. They are usua... |
|
T38802 |
Trimethobenzamide
|
Ro 2-9578 free base,Trimethobenzamide |
|
|
Trimethobenzamide (Ro 2-9578 free base) is a D2 receptor antagonist and an antiemetic agent. Primarily utilized to mitigate the occurrence of nausea and vomiting, trimethobenzamide effectively blocks the D2 receptor. |
|
T68371 |
Rolapitant hydrochloride hydrate
|
|
|
|
Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant compe... |
|
T72820 |
(R)-Casopitant
|
(R)-GW679769 |
|
|
(R)-Casopitant ((R)-GW679769), an isomer of Casopitant, functions as an NK(1)-receptor antagonist. It has applications in the study of chemotherapy-induced nausea and vomiting [1] [2]. |
|
T32171 |
Iodoalphionic acid
|
NSC 11854,NSC-11854,Pheniodolum,NSC11854,Tenamid |
|
|
Iodoalphionic acid is the contrast medium for gallbladder examination. It is rarely found in the colon and can rarely masked the gallbladder. The density of the shadow from Iodoalphionic acid was greater than that produc... |
|
T31194 |
Dalapon
|
Basfapon B,Dowpon M,Dawpon-Rae |
|
|
Dalapon is a selective herbicide used to control perennial grasses. The major use of dalapon is on food crops including sugarcane and sugar beets. Its use is no longer authorized in France. The National Institute for Occ... |
