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AChE

Acetylcholinesterase, also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T22545 Acephate 30560-19-1 98%
Acephate (Orthene) is an anticholinesterase insecticide with a weak inhibitory effect on AChE in rats, but it can effectively inhibit AChE in cockroaches.
T8585 TA-03 5778-80-3 98%
TA-03 (7-Meota) is a potent inhibitor of AChE in treatment of cognitive manifestation of AD.
T72112 Clozapine N-oxide dihydrochloride 2250025-93-3 98%
Clozapine N-oxide dihydrochloride is a derivative of Clozapine and an agonist of human muscarinic design receptors (DREADDs) that crosses the blood-brain barrier...
T14194 β-NETA 31059-54-8 98%
β-NETA (α-NETA) is a stable, noncompetitive, slowly reversible choline acetyltransferase (ChAT) inhibitor with an IC50 of 9 μM and is a potent chemokine-like rec...
TC0022 Desoxypeganine 495-59-0 98%
Desoxypeganine (Deoxypeganine) is an inhibitor of cholinesterase. It acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine ox...
TN1403 Arjunolic acid 465-00-9 98%
Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the devel...
T0338 Minaprine 25905-77-5 98%
Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
Fr16605 Lupinine 486-70-4
Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Lora...
T0731 Diethyltoluamide 134-62-3
Diethyltoluamide (DEET) is the most general active composition in insect repellents.
T19084 1-Naphthyl acetate 830-81-9
1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages. 1-Naphthyl acetate is a potent chromogenic substrate for the det...
TN2298 Vincosamide 23141-27-7
Vincosamide is an alkaloid from Psychotria leiocarpa extract, inhibits the acetylcholinesterase (AChE) activity with anti-inflammatory activity. Vincosamide can ...
TN2130 Manghaslin 55696-57-6
Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenoli...
T0269 Dichlorisone Acetate 79-61-8
Dichlorisone Acetate (Diloderm) is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity.
T5S2254 Swertianolin 23445-00-3
1. Swertianolin (Bellidifolin-8-O-Glucoside), mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic mar...
T2319 Acotiamide monohydrochloride trihydrate 773092-05-0
Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancin...
T3S1612 Kuwanon G 75629-19-5
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective ...
TN1528 Cotoin 479-21-0 100%
Cotoin is a natural product isolated from the stem bark of Garcinia virgate.Cotoin has antispasmodic activity and reduces the tone and contraction of isolated ra...
T2759 Loganin 18524-94-2 100%
Loganin (Loganoside), an iridoid glucoside, has been reported to be an inhibitor of Cox-1 and also noted to suppress TNF-α formation. This compound also has disp...
T34399 Rovatirelin 204386-76-5 100%
Rovatirelin (S-0373) is a newly synthesized thyrotropin-releasing hormone (TRH) analog that ameliorates cytosine arabinoside-induced motor dysfunction in a rat m...
T1635 Fenchlorphos 299-84-3 100%
Fenchlorphos (Dermafos) is a cholinesterase inhibitor, used as an insecticide.
Acephate
T22545
Acephate (Orthene) is an anticholinesterase insecticide with a weak inhibitory effect on AChE in rats, but it can effectively inhibit AChE in cockroaches.
TA-03
T8585
TA-03 (7-Meota) is a potent inhibitor of AChE in treatment of cognitive manifestation of AD.
Clozapine N-oxide dihydrochloride
T72112
Clozapine N-oxide dihydrochloride is a derivative of Clozapine and an agonist of human muscarinic design receptors (DREADDs) that crosses the blood-brain barrier...
β-NETA
T14194
β-NETA (α-NETA) is a stable, noncompetitive, slowly reversible choline acetyltransferase (ChAT) inhibitor with an IC50 of 9 μM and is a potent chemokine-like rec...
Desoxypeganine
TC0022
Desoxypeganine (Deoxypeganine) is an inhibitor of cholinesterase. It acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine ox...
Arjunolic acid
TN1403
Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the devel...
Minaprine
T0338
Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
Lupinine
Fr16605
Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Lora...
Diethyltoluamide
T0731
Diethyltoluamide (DEET) is the most general active composition in insect repellents.
1-Naphthyl acetate
T19084
1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages. 1-Naphthyl acetate is a potent chromogenic substrate for the det...
Vincosamide
TN2298
Vincosamide is an alkaloid from Psychotria leiocarpa extract, inhibits the acetylcholinesterase (AChE) activity with anti-inflammatory activity. Vincosamide can ...
Manghaslin
TN2130
Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenoli...
Dichlorisone Acetate
T0269
Dichlorisone Acetate (Diloderm) is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity.
Swertianolin
T5S2254
1. Swertianolin (Bellidifolin-8-O-Glucoside), mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic mar...
Acotiamide monohydrochloride trihydrate
T2319
Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancin...
kuwanon G
T3S1612
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective ...
Cotoin
TN1528
Cotoin is a natural product isolated from the stem bark of Garcinia virgate.Cotoin has antispasmodic activity and reduces the tone and contraction of isolated ra...
Loganin
T2759
Loganin (Loganoside), an iridoid glucoside, has been reported to be an inhibitor of Cox-1 and also noted to suppress TNF-α formation. This compound also has disp...
Rovatirelin
T34399
Rovatirelin (S-0373) is a newly synthesized thyrotropin-releasing hormone (TRH) analog that ameliorates cytosine arabinoside-induced motor dysfunction in a rat m...
Fenchlorphos
T1635
Fenchlorphos (Dermafos) is a cholinesterase inhibitor, used as an insecticide.
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