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GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T4500 ADX88178 1235318-89-4 98%
ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.
T3010 Xanthurenic Acid 59-00-7 98%
Xanthurenic Acid (8-Hydroxykynurenic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropi...
T3957 Farampator 211735-76-1 98%
Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.
T6871 L-Glutamic acid monosodium salt 142-47-2 98%
L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.
T9011 VU0155094 731006-86-3 98%
VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.
T20191 (-)-Camphoric acid 560-09-8 98%
(-)-Camphoric acid (L-Camphoric acid) is a less active enantiomer of Camphoric acid which induces GluR expression.
T20571 Cis-PDA 46026-75-9 98%
cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.
T13323 VU6012962 2313526-86-0 98%
VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).
T22638 CBiPES hydrochloride 856702-40-4 98%
CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of...
T22840 HexylHIBO 334887-43-3 98%
HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.
T1443 Memantine hydrochloride 41100-52-1 98%
Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparki...
T3479 (RS)-MCPG 146669-29-6 98%
(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.
T22711 DCB 6971-97-7 98%
DCB (3,3'-dichlorobenzaldazine) is an allosteric ligand for mGluR5 and shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB). DCB blocks the...
T3473 (S)-ATPO 252930-37-3 98%
(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
T41301 L-Cysteinesulfinic acid monohydrate 207121-48-0 98%
L-Cysteinesulfinic acid monohydrate is a potent agonist at rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92, 4.6, 3.9, 2.7, 4.0, and 3.94 for mG...
T13321 VU6005649 2137047-43-7 98%
VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).
T23303 S-Sulfo-L-cysteine sodium salt 7381-67-1 98%
S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.
T29135 VU0422288 1630936-95-6 98%
VU0422288 (ML396) is a potent orthosteric modulator of type III mGlu receptors (mGlus).VU0422288 shows inhibition of mGluR4, mGluR7, and mGluR8 in a calcium mobi...
T23259 (RS)-3-Hydroxyphenylglycine 31932-87-3 98%
PI-linked metabotropic glutamate receptors agonist
T22976 MFZ 10-7 1224431-15-5 98%
MFZ 10-7 is anegative allosteric modulator of the mGluR5.
ADX88178
T4500
ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.
Xanthurenic Acid
T3010
Xanthurenic Acid (8-Hydroxykynurenic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropi...
Farampator
T3957
Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.
L-Glutamic acid monosodium salt
T6871
L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.
VU0155094
T9011
VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.
(-)-Camphoric acid
T20191
(-)-Camphoric acid (L-Camphoric acid) is a less active enantiomer of Camphoric acid which induces GluR expression.
cis-PDA
T20571
cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.
VU6012962
T13323
VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).
CBiPES hydrochloride
T22638
CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of...
HexylHIBO
T22840
HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.
Memantine hydrochloride
T1443
Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparki...
(RS)-MCPG
T3479
(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.
DCB
T22711
DCB (3,3'-dichlorobenzaldazine) is an allosteric ligand for mGluR5 and shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB). DCB blocks the...
(S)-ATPO
T3473
(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
L-Cysteinesulfinic acid monohydrate
T41301
L-Cysteinesulfinic acid monohydrate is a potent agonist at rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92, 4.6, 3.9, 2.7, 4.0, and 3.94 for mG...
VU6005649
T13321
VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).
S-Sulfo-L-cysteine sodium salt
T23303
S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.
VU0422288
T29135
VU0422288 (ML396) is a potent orthosteric modulator of type III mGlu receptors (mGlus).VU0422288 shows inhibition of mGluR4, mGluR7, and mGluR8 in a calcium mobi...
(RS)-3-Hydroxyphenylglycine
T23259
PI-linked metabotropic glutamate receptors agonist
MFZ 10-7
T22976
MFZ 10-7 is anegative allosteric modulator of the mGluR5.
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