MAGL

Monoacylglycerol lipase, also known as MAG lipase, acylglycerol lipase, MAGL, MGL or MGLL is an enzyme that, in humans, is encoded by the MGLL gene. MAGL is a 33-kDa, membrane-associated member of the serine hydrolase superfamily and contains the classical GXSXG consensus sequence common to most serine hydrolases. The catalytic triad has been identified as Ser122, His269, and Asp239.

Cat. No.	製品名	CAS No.	Purity
T17260	WWL70	947669-91-2	98%
T17260	WWL70 is a selective alpha/beta hydrolase domain 6 inhibitors (IC50: 70 nM).
T11784	KT182	1402612-62-7	98%
T11784	KT182 is a selective and potent inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells.
T15635	JZP-430	1672691-74-5	98%
T15635	JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM). It also shows ~230-fold selectivity over fatty...
T22171	WWL123	1338575-41-9	98%
T22171	WWL123 is a potent and selective ABHD6 inhibitor (IC50=430 nM). WWL123 crosses the blood-brain-barrier and inhibits ABHD6 in brain parenchyma. ABHD6 blockade by ...
T8994	ML-226	2055172-43-3	98%
T8994	ML226 is a α/β hydrolase domain-containing protein 11 (ABHD11) inhibitor that inhibits ABHD11 in vitro and in situ.
T9374	AA38-3	65815-76-1	98%
T9374	AA38-3 inhibites three SHs (ABHD6, ABHD11, and FAAH)