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Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T36944 Ara-G 38819-10-2 98%
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, wh...
TQ0245 Sapacitabine 151823-14-2 98%
Sapacitabine is a nucleoside analog prodrug with antitumor activity.
T9726 2’-OMe-Guanosine 2140-71-8 98%
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
T38958 DMT-2′Fluoro-dU Phosphoramidite 146954-75-8 98%
DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.
T9727 2'-Fluoro-2'-Deoxyadenosine 64183-27-3 98%
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-De...
T38238 2'-Deoxy-2'-fluorocytidine 10212-20-1 98%
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine ...
TNU0839 1,4-Dideoxy-1,4-epithio-D-ribitol 190315-43-6 98%
1,4-Dideoxy-1,4-epithio-D-ribitol is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of ant...
TNU0802 5-Bromo-2’,3’,5’-tri-O-acetyluridine 105659-32-3 98%
5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that may be used to explore the amelioration of Alzheimer's disease and Parkinson's disease.Vi...
T20102 8-Azahypoxanthine 2683-90-1 98%
8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.
T36866 3-Deazauridine 23205-42-7 98%
3-Deazauridine (NSC-126849) is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Tr...
T19083 1-Methylinosine 2140-73-0 98%
1-Methylinosine (N1-Methylinosine) is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA and has a role as a metabolite.
T1378 Tegafur 17902-23-7 98%
Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity. Tegafur is a prodrug that is gradually converted to fluorouracil ...
TNU0178 2'-O-(2-Azidoethyl)adenosine 2226475-42-7 98%
2'-O-(2-azidoethyl)adenosine is a purine nucleoside analog with potential antitumor activity. The activity of 2'-O-(2-azidoethyl)adenosine was associated with in...
T38237 2′-O-Methylcytidine 2140-72-9 98%
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replic...
T38236 2′-Deoxy-2′-fluoroguanosine 78842-13-4 98%
2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhib...
T13659 DMTr-LNA-5MeU-3-CED-phosphoramidite 206055-75-6
DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.
T1120 Dacarbazine 4342-03-4 100%
Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.
T36971 5-Ethynyluridine 69075-42-9 100%
5-Ethynyluridine is a clickable form of uridine.1It is incorporated into cellular RNA, but not DNA, and has been used to detect transcriptionin vitroandin vivo. ...
T7319 7-Methylguanosine 20244-86-4 100%
7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor (IC50 : 87.8 ± 7.5 μM).
T8648 6-AZATHYMINE 932-53-6 100%
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine,...
Ara-G
T36944
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, wh...
Sapacitabine
TQ0245
Sapacitabine is a nucleoside analog prodrug with antitumor activity.
2’-OMe-Guanosine
T9726
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
DMT-2′Fluoro-dU Phosphoramidite
T38958
DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.
2'-Fluoro-2'-Deoxyadenosine
T9727
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-De...
2'-Deoxy-2'-fluorocytidine
T38238
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine ...
1,4-Dideoxy-1,4-epithio-D-ribitol
TNU0839
1,4-Dideoxy-1,4-epithio-D-ribitol is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of ant...
5-Bromo-2’,3’,5’-tri-O-acetyluridine
TNU0802
5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that may be used to explore the amelioration of Alzheimer's disease and Parkinson's disease.Vi...
8-Azahypoxanthine
T20102
8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.
3-Deazauridine
T36866
3-Deazauridine (NSC-126849) is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Tr...
1-Methylinosine
T19083
1-Methylinosine (N1-Methylinosine) is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA and has a role as a metabolite.
Tegafur
T1378
Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity. Tegafur is a prodrug that is gradually converted to fluorouracil ...
2'-O-(2-Azidoethyl)adenosine
TNU0178
2'-O-(2-azidoethyl)adenosine is a purine nucleoside analog with potential antitumor activity. The activity of 2'-O-(2-azidoethyl)adenosine was associated with in...
2′-O-Methylcytidine
T38237
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replic...
2′-Deoxy-2′-fluoroguanosine
T38236
2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhib...
DMTr-LNA-5MeU-3-CED-phosphoramidite
T13659
DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.
Dacarbazine
T1120
Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.
5-Ethynyluridine
T36971
5-Ethynyluridine is a clickable form of uridine.1It is incorporated into cellular RNA, but not DNA, and has been used to detect transcriptionin vitroandin vivo. ...
7-Methylguanosine
T7319
7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor (IC50 : 87.8 ± 7.5 μM).
6-AZATHYMINE
T8648
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine,...
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