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Nucleoside Antimetabolite/Analog

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T36944 Ara-G 38819-10-2 98%
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, wh...
T9726 2’-OMe-Guanosine 2140-71-8 98%
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
TNU1205 2’-Deoxy-N4-methylcytidine 22882-02-6 98%
2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.
T38958 DMT-2′Fluoro-dU Phosphoramidite 146954-75-8 98%
DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.
T9727 2'-Fluoro-2'-Deoxyadenosine 64183-27-3 98%
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-De...
T38238 2'-Deoxy-2'-fluorocytidine 10212-20-1 98%
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine ...
T32826 LNA-Adenosine 206055-70-1 98%
LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.
T8648 6-AZATHYMINE 932-53-6 98%
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine,...
TNU0839 1,4-Dideoxy-1,4-epithio-D-ribitol 190315-43-6 98%
1,4-Dideoxy-1,4-epithio-D-ribitol is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of ant...
T20102 8-Azahypoxanthine 2683-90-1 98%
8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.
T36866 3-Deazauridine 23205-42-7 98%
3-Deazauridine (NSC-126849) is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Tr...
T13659 DMTr-LNA-5MeU-3-CED-phosphoramidite 206055-75-6 98%
DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.
T19083 1-Methylinosine 2140-73-0 98%
1-Methylinosine (N1-Methylinosine) is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA and has a role as a metabolite.
T6069 Gemcitabine hydrochloride 122111-03-9 98%
Gemcitabine hydrochloride (LY 188011 hydrochloride) is a DNA synthesis inhibitor (IC50s: 12, 18, 40, 92.7, 89.3 in Capan2, BxPC-3, Mia Paca-2, PANC-1, and PL-45 ...
T1339 5-Azacytidine 320-67-2 98%
5-Azacytidine (Ladakamycin) , a pyrimidine nucleoside analogue of cytidine, blocks DNA methylation with antineoplastic activity.
T1378 Tegafur 17902-23-7 98%
Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity. Tegafur is a prodrug that is gradually converted to fluorouracil ...
TNU1431 (S)-GNA-T-phosphoramidite 168332-13-6 98%
(S)-GNA-T-phosphoramidite is a nucleoside analog commonly used in the synthesis of other active compounds.
TNU1119 N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite 207347-42-0 98%
N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analog with potential vasodilator activity and anticancer activity for cancer...
TNU0178 2'-O-(2-Azidoethyl)adenosine 2226475-42-7 98%
2'-O-(2-azidoethyl)adenosine is a purine nucleoside analog with potential antitumor activity. The activity of 2'-O-(2-azidoethyl)adenosine was associated with in...
T3658 Trifluridine/tipiracil hydrochloride mixture 733030-01-8 98%
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a mola...
Ara-G
T36944
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, wh...
2’-OMe-Guanosine
T9726
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
2’-Deoxy-N4-methylcytidine
TNU1205
2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.
DMT-2′Fluoro-dU Phosphoramidite
T38958
DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.
2'-Fluoro-2'-Deoxyadenosine
T9727
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-De...
2'-Deoxy-2'-fluorocytidine
T38238
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine ...
LNA-Adenosine
T32826
LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.
6-AZATHYMINE
T8648
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine,...
1,4-Dideoxy-1,4-epithio-D-ribitol
TNU0839
1,4-Dideoxy-1,4-epithio-D-ribitol is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of ant...
8-Azahypoxanthine
T20102
8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.
3-Deazauridine
T36866
3-Deazauridine (NSC-126849) is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Tr...
DMTr-LNA-5MeU-3-CED-phosphoramidite
T13659
DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.
1-Methylinosine
T19083
1-Methylinosine (N1-Methylinosine) is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA and has a role as a metabolite.
Gemcitabine hydrochloride
T6069
Gemcitabine hydrochloride (LY 188011 hydrochloride) is a DNA synthesis inhibitor (IC50s: 12, 18, 40, 92.7, 89.3 in Capan2, BxPC-3, Mia Paca-2, PANC-1, and PL-45 ...
5-Azacytidine
T1339
5-Azacytidine (Ladakamycin) , a pyrimidine nucleoside analogue of cytidine, blocks DNA methylation with antineoplastic activity.
Tegafur
T1378
Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity. Tegafur is a prodrug that is gradually converted to fluorouracil ...
(S)-GNA-T-phosphoramidite
TNU1431
(S)-GNA-T-phosphoramidite is a nucleoside analog commonly used in the synthesis of other active compounds.
N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
TNU1119
N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analog with potential vasodilator activity and anticancer activity for cancer...
2'-O-(2-Azidoethyl)adenosine
TNU0178
2'-O-(2-azidoethyl)adenosine is a purine nucleoside analog with potential antitumor activity. The activity of 2'-O-(2-azidoethyl)adenosine was associated with in...
Trifluridine/tipiracil hydrochloride mixture
T3658
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a mola...
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