Reactive Oxygen Species

Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion. ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.

Cat. No.	製品名	CAS No.	Purity
T3429	Protopine	130-86-9	98%
T3429	Protopine is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.
TQ0212	Glucoraphanin	21414-41-5	98%
TQ0212	Glucoraphanin, the precursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, has antioxidant activity.
T3496	Buprofezin	69327-76-0	98%
T3496	Buprofezin is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops.
T5852	Canthaxanthin	514-78-3	98%
T5852	Canthaxanthin is a red-orange carotenoid that belongs to the xanthophyll group. This naturally occurring pigment is present in bacteria, algae and some fungi.
TN1141	Isodeoxyelephantopin	38927-54-7	98%
TN1141	Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apopt...
T37688	Cyfluthrin	68359-37-5	98%
T37688	Cyfluthrin is a pyrethroid insecticide and a modulator of voltage-gated sodium channels (Nav).1,2It slowly activates rat recombinant Nav1.8 channels, delays inac...
TN7108	Urolithin C	165393-06-6	98%
TN7108	Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
T8193	α-Thujone	546-80-5	98%
T8193	Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
T4287	Succinobucol	216167-82-7	98%
T4287	Succinobucol is a novel phenolic antioxidant small molecule with anti-oxidant and anti-inflammatory properties. It designed to treat atherosclerosis of the blood...
T5A2461	Bufotalin	471-95-4	98%
T5A2461	1. Bufotaline is a kind of poisonous secretions of toads.
T15458	H2DCFDA	4091-99-0	98%
T15458	H2DCFDA is a cell-permeable probe. Which is used to detect intracellular reactive oxygen species (ROS).
T7486	Imeglimin hydrochloride	775351-61-6	98%
T7486	Imeglimin hydrochloride prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration.
T38310	Luciferase-IN-1	10205-56-8	98%
T38310	Luciferase-IN-1 is a luciferase inhibitor that can be used to study bacterial and fungal infections.
T1684	Nitisinone	104206-65-7	98%
T1684	Nitisinone(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor.
T1710	Trolox	53188-07-1	98%
T1710	Troloxa is a vitamin E analogue, used in reducing oxidative stress or damage.
T67498	3-Amino-1,2,4-triazole	61-82-5	98%
T67498	3-Amino-1,2,4-triazole is an inhibitor of catalase, capable of inducing the compensatory mechanism for hydrogen peroxide detoxification. This mechanism involves ...
T2871	Quercitrin	522-12-3	98%
T2871	Quercitrin is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities. Quercitrin can be found in a number of food items such a...
T20578	Maclurin	519-34-6	98%
T20578	Maclurin is a phenolic component of mulberry twigs, exerts anti-metastatic effects. Maclurin effectively protects against OH-induced damages to DNA and MSCs and ...
T38155	N-Acetyl-D-cysteine	26117-28-2	98%
T38155	N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway[1]...
T17155	Trabectedin	114899-77-3	98%
T17155	Trabectedin a tetrahydroisoquinoline alkaloid. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbon...