T2S1040 |
Jolkinolide B
|
37905-08-1
|
98%
|
|
Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud. Jolkinolide B induces apoptosis in cancer cells. Jolkinolide B can...
|
T4S2126 |
Ginkgetin
|
481-46-9
|
98%
|
|
1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against...
|
T35544 |
ML115
|
912798-42-6
|
98%
|
|
Signal transducer and activator of transcription 3 (STAT3) is a cytokine-inducible transcription factor with roles in inflammation and cancer. ML115 is an isoxaz...
|
T2S1975 |
Ponicidin
|
52617-37-5
|
98%
|
|
Ponicidin has anti-leukemia, immunoregulatory and anti-inflammatory functions, it also has anti-viral function especially in the upper respiratory tract infectio...
|
TN1673 |
Garcinone C
|
76996-27-5
|
98%
|
|
Garcinone C is a xanthone derivative extracted from Garcinia oblongifolia Champ with anti-inflammatory, astringency, and granulation-promoting activities. Garcin...
|
T5S0993 |
Kurarinone
|
34981-26-5
|
98%
|
|
Kurarinone, a flavanoid derived from shrub Sophora flavescens,Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong ...
|
T4S0145 |
Corylifol A
|
775351-88-7
|
98%
|
|
1. Corylifol A displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. ...
|
T5S0168 |
Atractylenolide II
|
73069-14-4
|
98%
|
|
1. Atractylenolide II has antimelanoma effect by inhibiting STAT3 signalling. 2. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation , ERK ...
|
T4615 |
Balsalazide sodium hydrate
|
150399-21-6
|
98%
|
|
Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing pr...
|
TN4379 |
Kansuinine A
|
57701-86-7
|
98%
|
|
Kansuinine A possesses analgesic props, it also shows NGF inducing activity.
|
T9945 |
MNK8
|
2055078-49-2
|
98%
|
|
3-methyl-6- (naphthalen-1-yl)pyrimidine-2,4(1H, 3H)-dione is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth...
|
T1563 |
Nifuroxazide
|
965-52-6
|
98%
|
|
Nifuroxazide is an orally available and cell-permeable nitrofuran-based antidiarrheal agent. It has the inhibitory effect against the activation of cellular STAT...
|
T77672 |
JI069
|
850019-35-1
|
98%
|
|
JI069 (WAY-354189) is a potent STAT3 inhibitor that inhibits gp130 signaling by inducing dissociation between gp130 and JAK1.
|
T4034 |
Solamargine
|
20311-51-7
|
98%
|
|
Solamargine is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL); has been shown to inhibit growth...
|
T13950 |
UC-514321
|
299420-83-0
|
98%
|
|
UC-514321 is a structural analog of NSC370284 and has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity.
|
TP1433 |
CMD178 TFA
|
TP1433
|
98%
|
|
CMD178 (TFA) is a lead peptide that consistently reduces the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling.
|
T8378 |
AS2863619
|
2241300-51-4
|
98%
|
|
AS2863619 is an orally active inhibitor of cyclin-dependent kinase 8 (CDK8) and CDK19 (IC50s of 0.61 nM and 4.28 nM, respectively).
|
TJS1779 |
Protosappanin A
|
102036-28-2
|
98%
|
|
Protosappanin A has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammat...
|
T4672 |
Brevilin A
|
16503-32-5
|
98%
|
|
Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor a...
|
T1038 |
Fludarabine
|
21679-14-1
|
98%
|
|
Fludarabine is a nucleic acid synthesis Inhibitor and a STAT1 activation inhibitor.
|