Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist with an EC50 for Apelin receptors of 0.012 µM.(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5- methylpyrimidin-2-yl)butane-2-sulfonamide is used in the treatment of heart failure, atherosclerosis, obesity, diabetes mellitus, amyotrophic lateral sclerosis, coronary artery disease, hypertension, stroke and myocardial infarction.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 45,000 |
5 mg | 在庫あり | ¥ 99,000 |
10 mg | 在庫あり | ¥ 146,000 |
25 mg | お問い合わせ | ¥ 226,500 |
50 mg | お問い合わせ | ¥ 312,500 |
説明 | (2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist with an EC50 for Apelin receptors of 0.012 µM.(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5- methylpyrimidin-2-yl)butane-2-sulfonamide is used in the treatment of heart failure, atherosclerosis, obesity, diabetes mellitus, amyotrophic lateral sclerosis, coronary artery disease, hypertension, stroke and myocardial infarction. |
ターゲット&IC50 | Apelin receptor:0.012 µM |
分子量 | 523.61 |
分子式 | C25H29N7O4S |
CAS No. | 2049979-31-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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(2R,3S)-Azelaprag 2049979-31-7 GPCR/G Protein Apelin receptor Azelaprag (2R,3S)N(4(2,6dimethoxyphenyl)5(5methylpyridin3yl)4H1,2,4triazol3yl)3(5methylpyrimidin2yl)butane2sulfonamide Inhibitor inhibitor inhibit