Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771. ARV-771 is a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 9,000 | |||
25 mg | 在庫あり | ¥ 16,500 | |||
50 mg | 在庫あり | ¥ 25,000 | |||
100 mg | 在庫あり | ¥ 37,500 | |||
200 mg | 在庫あり | ¥ 56,000 | |||
500 mg | 在庫あり | ¥ 91,500 |
説明 | (S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771. ARV-771 is a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM. |
別名 | VHL ligand 2, E3 ligase Ligand 1A |
分子量 | 444.59 |
分子式 | C23H32N4O3S |
CAS No. | 1948273-02-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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(S,R,S)-AHPC-Me 1948273-02-6 PROTAC Ligand for E3 Ligase AHPC-Me VHL ligand 2 VHL ligand-2 VHL ligand2 Inhibitor inhibit Ligands for E3 Ligase (S,R,S) AHPC Me (S,R,S)AHPCMe E3 ligase-recruiting Moiety E3 ligase Ligand 1A inhibitor