Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is a chemical compound utilized in the synthesis of ARV-771, an exceptionally potent BET protein degrader. This compound selectively degrades BET protein in cells resistant to castration, exhibiting a remarkable DC50 <1 nM. Recognized as VHL ligand 2 hydrochloride, (S,R,S)-AHPC-Me hydrochloride serves as the VHL ligand derived from (S,R,S)-AHPC for the recruitment of von Hippel-Lindau (VHL) protein.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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10 mg | 在庫あり | ¥ 8,000 | |||
25 mg | 在庫あり | ¥ 13,000 | |||
50 mg | 在庫あり | ¥ 19,000 | |||
100 mg | 在庫あり | ¥ 28,000 |
説明 | (S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is a chemical compound utilized in the synthesis of ARV-771, an exceptionally potent BET protein degrader. This compound selectively degrades BET protein in cells resistant to castration, exhibiting a remarkable DC50 <1 nM. Recognized as VHL ligand 2 hydrochloride, (S,R,S)-AHPC-Me hydrochloride serves as the VHL ligand derived from (S,R,S)-AHPC for the recruitment of von Hippel-Lindau (VHL) protein. |
別名 | VHL ligand 2 hydrochloride, E3 ligase Ligand 1 |
分子量 | 481.05 |
分子式 | C23H33ClN4O3S |
CAS No. | 1948273-03-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 62 mg/mL(128.88 mM)
You can also refer to dose conversion for different animals. 詳細
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(S,R,S)-AHPC-Me hydrochloride 1948273-03-7 Others PROTAC Ligand for E3 Ligase VHL ligand 2 Hydrochloride Ligands for E3 Ligase VHL ligand 2 hydrochloride (S,R,S)AHPCMe hydrochloride E3 ligase-recruiting Moiety (S,R,S) AHPC Me hydrochloride E3 ligase Ligand 1 AHPC-Me Hydrochloride VHL ligand2 VHL ligand 2 inhibit VHL ligand-2 Inhibitor inhibitor