keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
β-Amyloid (25-35) (Aβ25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 15,000 | |||
5 mg | 在庫あり | ¥ 43,500 | |||
10 mg | 在庫あり | ¥ 66,500 | |||
25 mg | 在庫あり | ¥ 119,500 | |||
50 mg | 在庫あり | ¥ 172,500 | |||
100 mg | 在庫あり | ¥ 243,500 |
説明 | β-Amyloid (25-35) (Aβ25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells. |
In vitro | The amino acid sequence of β-Amyloid (25-35) is NH2-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-COOH, where the first Gly represents the amino acid 25 and the last Met represents the amino acid 35 and it is also investigated in gel state for the first time. Amyloid beta-peptide(25-35) induces apoptotic effects on isolated brain mitochondria and the redox state of methionine-35, plays a key role in the induction of programmed cellular death pathways and toxic events[2]. Comparative studies are also carried out using vibrational absorption and ECD. The conformational preference of Aβ(25-35) peptide film is also investigated using vibrational absorption and VCD spectroscopy[1]. |
In vivo | The Alzheimer' s disease (AD) model group present with spatial learning and memory impairments. CDS and donepezil administration significantly ameliorate the Aβ25–35 peptide-induced memory impairment in both Morris water maze (P? |
別名 | β-Amyloid peptide(25-35), Aβ25-35, Amyloid beta-peptide(25-35) |
分子量 | 1060.27 |
分子式 | C45H81N13O14S |
CAS No. | 131602-53-4 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 3.33 mg/mL (3.14 mM), Sonication is recommended.
DMSO: 97 mg/mL (91.49 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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