Powder: -20°C for 3 years | In solvent: -80°C for 1 year
4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .
説明 | 4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a . |
ターゲット&IC50 | HCV NS3/4A:500 μM |
In vitro | A novel and highly conserved binding site at the interface of the protease and helicase domains of the Hepatitis C Virus (HCV) NS3 protein has been identified. Binding of 4-Phenoxybenzylamine to this allosteric site inhibits NS3 function by stabilizing an inactive conformation, introducing a new class of direct-acting antiviral agents. |
分子量 | 199.25 |
分子式 | C13H13NO |
CAS No. | 107622-80-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (150.56 mM)
You can also refer to dose conversion for different animals. 詳細
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4-Phenoxybenzylamine 107622-80-0 Microbiology/Virology Proteases/Proteasome HCV Protease inhibit Inhibitor HCV 4Phenoxybenzylamine Hepatitis C virus 4 Phenoxybenzylamine inhibitor