keep away from direct sunlight,store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Arbutamine (GP 21213) is a novel potent non-selective beta-adrenoceptor agonist with alpha-1-sympathomimetic activity.Arbutamine promotes cardiac stress and increases heart rate, cardiac contractility.Arbutamine can be used to study cardiac stress and coronary artery disease
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 91,500 |
5 mg | 在庫あり | ¥ 223,000 |
10 mg | 在庫あり | ¥ 271,000 |
25 mg | 在庫あり | ¥ 363,000 |
50 mg | 在庫あり | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | Arbutamine (GP 21213) is a novel potent non-selective beta-adrenoceptor agonist with alpha-1-sympathomimetic activity.Arbutamine promotes cardiac stress and increases heart rate, cardiac contractility.Arbutamine can be used to study cardiac stress and coronary artery disease |
In vitro | The affinity constants (Ka) of arbutamine and isoproterenol for cardiac beta1-adrenergic receptors, as determined by competition binding assays, were found to be 7.32 and 6.04, respectively[3]. |
In vivo | In the electrical stimulation of the left atrium of rats, Arbutamine increases contractility. The pD2 values (logarithm of the dose producing 50% of the maximum response) for Arbutamine and isoproterenol are 8.45 +/- 0.15 and 8.55 +/- 0.02, respectively. In the guinea pig trachea, Arbutamine and isoproterenol induced a concentration-dependent relaxation, which was inhibited by propranolol[3]. |
別名 | GP 21213 |
分子量 | 317.38 |
分子式 | C18H23NO4 |
CAS No. | 128470-16-6 |
keep away from direct sunlight,store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Arbutamine 128470-16-6 GPCR/G Protein Neuroscience Adrenergic Receptor GP 21213 Inhibitor inhibitor inhibit