Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
In vitro | Administering Bay 65-1942 before ischemia significantly reduces the size of left ventricular infarcts compared to controls given a placebo. This effect is evident at every measured interval, with notable reductions in the infarct-to-area-at-risk (AAR) ratio when Bay 65-1942 is administered before ischemia, at reperfusion, and after 2 hours of reperfusion, showing significant differences when compared with the placebo group (P<0.05 for each comparison). Furthermore, animals pretreated with Bay 65-1942 exhibited substantially lower creatine kinase-MB (CK-MB) levels, indicating less cardiac muscle damage, compared to those not receiving the compound prior to ischemia-reperfusion (IR), highlighting its protective role against heart tissue damage (P<0.05 vs. placebo). |
分子量 | 395.45 |
分子式 | C22H25N3O4 |
CAS No. | 600734-02-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Bay 65-1942 free base 600734-02-9 NF-Κb IκB/IKK Bay 65 1942 free base Bay 651942 free base Bay 65-1942 Inhibitor inhibitor inhibit