store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer drugs in multidrug-resistant cells.The Ki values of Benzquinamide for α2A, α2B, and α2C adrenergic receptor (α2-AR) were 1,365, 691, and 545 nM, respectively. 545 nM, respectively.
説明 | Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer drugs in multidrug-resistant cells.The Ki values of Benzquinamide for α2A, α2B, and α2C adrenergic receptor (α2-AR) were 1,365, 691, and 545 nM, respectively. 545 nM, respectively. |
ターゲット&IC50 | α2A:1,365 nM (Ki), α2B:691 nM (Ki), α2C:545 nM (Ki) |
別名 | BZQ, P2647, Benzoquinamide |
分子量 | 404.5 |
分子式 | C22H32N2O5 |
CAS No. | 63-12-7 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Benzquinamide 63-12-7 GPCR/G Protein Neuroscience Adrenergic Receptor P-2647 P 2647 BZQ P2647 Benzoquinamide Inhibitor inhibitor inhibit