store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CBS9106 (SL-801) is a reversible oral CRM1 inhibitor with CRM1 degrading and antitumor activity.CBS9106 inhibits CRM1-dependent nuclear export and reduces CRM1 protein levels.CBS9106 inhibits tumor growth and prolongs the survival of mice bearing tumor xenografts.CBS9106 is an inhibitor of CRM1-dependent nuclear export and reduces CRM1 protein levels.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 67,500 |
5 mg | 在庫あり | ¥ 166,000 |
10 mg | 在庫あり | ¥ 226,500 |
25 mg | 在庫あり | ¥ 349,000 |
50 mg | 在庫あり | ¥ 454,500 |
説明 | CBS9106 (SL-801) is a reversible oral CRM1 inhibitor with CRM1 degrading and antitumor activity.CBS9106 inhibits CRM1-dependent nuclear export and reduces CRM1 protein levels.CBS9106 inhibits tumor growth and prolongs the survival of mice bearing tumor xenografts.CBS9106 is an inhibitor of CRM1-dependent nuclear export and reduces CRM1 protein levels. |
In vitro | MLN4924 also attenuated the nuclear accumulation of Ran-binding protein 1 (RanBP1) induced by CBS9106, as well as cell growth inhibition and apoptosis[1]. |
In vivo | Oral administration of CBS9106 significantly inhibited tumor growth and prolonged the survival time of mice bearing tumor xenografts without significantly reducing body weight [2]. |
別名 | Felezonexor, SL-801 |
分子量 | 419.83 |
分子式 | C18H21ClF3N3O3 |
CAS No. | 1076235-04-5 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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CBS9106 1076235-04-5 Membrane transporter/Ion channel CRM1 Felezonexor SL 801 SL-801 CBS 9106 CBS-9106 SL801 Inhibitor inhibitor inhibit