Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 8,500 | |||
2 mg | 在庫あり | ¥ 11,500 | |||
5 mg | 在庫あり | ¥ 16,500 | |||
10 mg | 在庫あり | ¥ 24,500 | |||
25 mg | 在庫あり | ¥ 44,000 | |||
50 mg | 在庫あり | ¥ 66,000 | |||
100 mg | 在庫あり | ¥ 99,500 | |||
500 mg | 在庫あり | ¥ 226,500 |
説明 | Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM). |
In vitro | Capmatinib hydrochloride blocks cell proliferation and migration or induces apoptosis in different types of cancer cells[1] |
別名 | INCB28060, Capmatinib hydrochloride(free base), INC280 |
分子量 | 448.89 |
分子式 | C23H18ClFN6O |
CAS No. | 1029714-89-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.48 mg/mL (9.99 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Capmatinib xHCl 1029714-89-3 Tyrosine Kinase/Adaptors c-Met/HGFR Apoptosis INCB28060 ATP competitive inhibit Inhibitor Capmatinib SNU-5 H441 INC 280 INC-280 Balb/c nu/nu mice Capmatinib hydrochloride(free base) U-87MG INC280 S114 INCB-28060 INCB 28060 orally active inhibitor