Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
2 mg | 約 5 days | ¥ 32,500 |
25 mg | 約6-8 週間 | ¥ 176,000 |
50 mg | 約6-8 週間 | ¥ 228,500 |
100 mg | 約6-8 週間 | ¥ 353,500 |
In vitro | Cimetropium reduces the release of labeled acetylcholine (ACh) elicited by electrical field stimulation, particularly when muscarinic autoinhibition is blocked, as observed in superfusion experiments using preparations preloaded with labeled choline [2]. Furthermore, it exhibits a powerful antimuscarinic action by inhibiting the contraction of longitudinal muscle preparations. As a competitive antagonist, Cimetropium Bromide effectively counteracts muscarinic-mediated contractions in isolated colonic preparations from various species, demonstrating affinity values (pA2) between 7.41 and 7.82 [1]. |
別名 | DA-3177 |
分子量 | 438.36 |
分子式 | C21H28BrNO4 |
CAS No. | 51598-60-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 50 mg/mL (114.06 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Cimetropium Bromide 51598-60-8 Neuroscience AChR DA 3177 DA3177 DA-3177 Inhibitor inhibitor inhibit