Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DPI 201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation resulting in a positive inotropic effect. DPI-201-106 also inhibits the inward and delayed rectifier potassium currents and L-type calcium current.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 11,000 | |||
10 mg | 在庫あり | ¥ 18,500 | |||
25 mg | 在庫あり | ¥ 37,500 | |||
50 mg | 在庫あり | ¥ 57,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 12,000 |
説明 | DPI 201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation resulting in a positive inotropic effect. DPI-201-106 also inhibits the inward and delayed rectifier potassium currents and L-type calcium current. |
In vitro | DPI 201-106(0.1 - 3 μM) produces concentration-dependent positive inotropic effects in guinea-pig and rat left atria, kitten, rabbit and guinea-pig papillary muscles and Langendorff perfused hearts of rabbits[2]. DPI 201-106 increases the Ca2+ sensitivity(EC50 = 0.2 nM) of skinned fibres from porcine trabecula septomarginalis[2]. |
In vivo | DPI 201-106(0.2 mg/kg i.v) administration increased left ventricular dP/dtmax in anesthetized dogs[3]. |
別名 | DPI-201-106 |
分子量 | 466.57 |
分子式 | C29H30N4O2 |
CAS No. | 97730-95-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (535.83 mM)
You can also refer to dose conversion for different animals. 詳細
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DPI 201-106 97730-95-5 Membrane transporter/Ion channel Sodium Channel SDZ 201106 SDZ201106 DPI 201 106 DPI 201106 Na channels SDZ-201106 DPI-201-106 inhibit DPI201-106 Na+ channels Inhibitor inhibitor