store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM).DSM265 inhibits the growth of Pf3D7 parasites and can be used for the treatment and prophylaxis of malaria infections.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 7,000 | |||
2 mg | 在庫あり | ¥ 9,500 | |||
5 mg | 在庫あり | ¥ 15,000 | |||
10 mg | 在庫あり | ¥ 20,500 | |||
25 mg | 在庫あり | ¥ 33,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 16,000 |
説明 | DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM).DSM265 inhibits the growth of Pf3D7 parasites and can be used for the treatment and prophylaxis of malaria infections. |
ターゲット&IC50 | PfDHODH:8.9 nM, P. falciparum (3D7 parasites):4.3 nM (EC50) |
In vivo | In NOD-scid IL-2Rγnull (NSG) mice (23-36 g), DSM265 (0.5 - 75 mg/kg; oral administration; twice daily; for 4 days) exhibited potent antimalarial activity[2]. |
別名 | PfSPZ |
分子量 | 415.33 |
分子式 | C14H12F7N5S |
CAS No. | 1282041-94-4 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 0.1 mg/mL (insoluble.)
Ethanol: 5 mg/mL (12.04 mM), Sonication is recommended.
DMSO: 30 mg/mL (72.23 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
DSM265 1282041-94-4 Metabolism Microbiology/Virology Dehydrogenase Parasite PfSPZ DSM-265 DSM 265 Inhibitor inhibitor inhibit