Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GSK256471 is a potent selective NK(3) antagonist that shows a high affinity for recombinant human (PK (I) value 8.9) and native guinea pig (PK (I) value 8.4) tachykinin NK(3) receptors. In vitro functional assessment showed that GSK256471 reduced the E(Max) response induced by neurokinin B, indicating insurgable antagonist pharmacology (PA (2)=9.2). GSK256471 may be a promising candidate for the treatment of schizophrenia.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約8-10 週間 | ¥ 486,500 |
50 mg | 約8-10 週間 | ¥ 638,000 |
100 mg | 約8-10 週間 | ¥ 849,500 |
説明 | GSK256471 is a potent selective NK(3) antagonist that shows a high affinity for recombinant human (PK (I) value 8.9) and native guinea pig (PK (I) value 8.4) tachykinin NK(3) receptors. In vitro functional assessment showed that GSK256471 reduced the E(Max) response induced by neurokinin B, indicating insurgable antagonist pharmacology (PA (2)=9.2). GSK256471 may be a promising candidate for the treatment of schizophrenia. |
別名 | GSK 256471, GSK-256471 |
分子量 | 499.62 |
分子式 | C29H29N3O3S |
CAS No. | 1133706-08-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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GSK256471 1133706-08-7 GSK 256471 GSK-256471 Inhibitor inhibitor inhibit