Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation.Hirsutenone exhibits anti-cancer, and anti-filarial effects, it may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity.
説明 | Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation.Hirsutenone exhibits anti-cancer, and anti-filarial effects, it may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity. |
植物由来 |
分子量 | 328.36 |
分子式 | C19H20O5 |
CAS No. | 41137-87-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Hirsutenone 41137-87-5 Angiogenesis Apoptosis Autophagy Cytoskeletal Signaling Immunology/Inflammation JAK/STAT signaling MAPK Microbiology/Virology NF-Κb PI3K/Akt/mTOR signaling Tyrosine Kinase/Adaptors ERK EGFR IL Receptor NF-κB PI3K Akt Antifection mTOR p53 Inhibitor inhibitor inhibit