Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ISX-1 inhibits adipogenesis and promotes osteoblastogenesis. ISX-1 can be used in studies about osteoporosis and osteopenia.
説明 | ISX-1 inhibits adipogenesis and promotes osteoblastogenesis. ISX-1 can be used in studies about osteoporosis and osteopenia. |
In vitro | In human bone marrow mesenchymal stem cells, ISX-1 (0-33 μM) inhibits the mRNA induction of PPARγ and FABP4 genes under the adipogenic differentiation of hBMSCs and promotes TCF/LEF-mediated gene transcription. ISX-1 inhibits the accumulation of intracellular lipid droplets(IC50 = 1.9 μM) and stimulated ALP activity(EC50 = 1.2 μM) in a dose-dependent manner[1]. |
別名 | ISX 1 |
分子量 | 302.35 |
分子式 | C14H14N4O2S |
CAS No. | 909207-35-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.02 mg/mL (10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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ISX-1 909207-35-8 Others ISX 1 ISX1 Inhibitor inhibitor inhibit