Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. It exhibits remarkable antibiotic activity, reflected by a minimal inhibitory concentration (MIC) value of 0.66 μg/mL.
説明 | JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. It exhibits remarkable antibiotic activity, reflected by a minimal inhibitory concentration (MIC) value of 0.66 μg/mL. |
In vitro | JH-LPH-33 effectively suppresses bacterial proliferation, demonstrating potent inhibition at a concentration of 1.6 μg/mL, and exhibits a minimum inhibitory concentration (MIC) of >64 μg/mL against E. coli. Furthermore, it shows significant activity against LpxH enzymes, with IC50 values of 0.026 μM for K. pneumoniae LpxH and 0.046 μM for E. coli LpxH, respectively. |
分子量 | N/A |
CAS No. | 2414590-04-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
JH-LPH-33 2414590-04-6 Others JHLPH33 JH LPH 33 Inhibitor inhibitor inhibit