keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Kisspeptin-10, human TFA is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 26,500 | |||
5 mg | 在庫あり | ¥ 88,500 | |||
10 mg | 在庫あり | ¥ 132,500 | |||
25 mg | 在庫あり | ¥ 212,500 | |||
50 mg | 在庫あり | ¥ 289,500 | |||
100 mg | 在庫あり | ¥ 385,500 |
説明 | Kisspeptin-10, human TFA is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression |
In vitro | KP-10-treatment significantly increased the expression of osteogenic genes, including mRNA and protein levels of BMP2, in C3H10T1/2 cells.?Moreover, KP-10 induced BMP2-luc activity and increased phosphorylation of Smad1/5/9.?In addition, NFATc4 specifically mediated KP-10-induced BMP2 gene expression.?However, KP-10 treatment did not induce expression of the BMP2 and Runx2 genes in GPR54-/- cells.?To examine whether KP-10 induced secretion of BMP2 to the culture medium, we used the conditioned-medium (C.M) of KP-10 treated medium on C3H10T1/2 cells.?Dlx5 and Runx2 expressions were higher in GPR54-/- cells treated with C.M than in those treated with KP-10[1]. |
分子量 | 1416.46 |
分子式 | C63H83N17O14.C2HF3O2 |
CAS No. | TP1345 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 4 mg/mL (2.82 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Kisspeptin-10, human (TFA)(374675-21-5,FREE) TP1345 Endocrinology/Hormones GPCR/G Protein GPR Kisspeptin Kisspeptin 10, human (TFA)(374675 21 5,FREE) Kisspeptin10, human (TFA)(374675215,FREE) Inhibitor inhibitor inhibit