keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Kyotorphin acetate is an endogenous peptide with analgesia activity and can be used as a biomarker of Alzheimer disease.
説明 | Kyotorphin acetate is an endogenous peptide with analgesia activity and can be used as a biomarker of Alzheimer disease. |
In vitro | The release of immunoreactive Met-enkephalin (I-ME) from the rat striatum was studied in vitro using a batch technique. A basal release of the order of 2-3% of total I-ME tissue content per 10 min was found. Kyotorphin produced dose-dependent I-ME release, with 0.5 mM maximal concentration causing 2-3-fold stimulation of release. This release was calcium-dependent. In concentrations up to 1 mM Kyotorphin did not change the basal release of [3H]noradrenaline, [3H]GABA, [3H]D-aspartate and immunoreactive beta-endorphin from various brain structures[3]. |
In vivo | Kyotorphin produced a naloxone-reversible potent analgesic effect, yet no inhibitory effect on electrically induced contractions of longitudinal muscle of the guinea pig ileum[1]. |
分子量 | 397.43 |
分子式 | C17H27N5O6 |
CAS No. | T20172L |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/ml (163.55 mM)
You can also refer to dose conversion for different animals. 詳細
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Kyotorphin acetate T20172L Metabolism Microbiology/Virology Antibacterial Endogenous Metabolite Kyotorphin Acetate Inhibitor inhibitor inhibit