Powder: -20°C for 3 years | In solvent: -80°C for 1 year
L-NIO dihydrochloride, a potent and non-selective NADPH-dependent nitric oxide synthase (NOS) inhibitor, consistently induces focal ischemic infarct in rats. It exhibits inhibitory constants (Kis) of 1.7, 3.9, and 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) forms, respectively.
説明 | L-NIO dihydrochloride, a potent and non-selective NADPH-dependent nitric oxide synthase (NOS) inhibitor, consistently induces focal ischemic infarct in rats. It exhibits inhibitory constants (Kis) of 1.7, 3.9, and 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) forms, respectively. |
ターゲット&IC50 | nNOS:ki: 1.7 μM , eNOS:3.9 μM (ki), iNOS:3.9 μM (ki) |
分子量 | 209.67 |
分子式 | C7H16ClN3O2 |
CAS No. | 159190-44-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 33.33 mg/mL (135.42 mM), Sonication is recommended.
H2O: 50 mg/mL (203.14 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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L-NIO dihydrochloride 159190-44-0 Immunology/Inflammation NOS L-NIO Dihydrochloride LNIO dihydrochloride L NIO dihydrochloride L-NIO Inhibitor inhibitor inhibit